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Heatr2
Gene Detail
Symbol

Name
ID
Heatr2
HEAT repeat containing 2
MGI:3616079
Feature Type
protein coding gene
Genetic Map
Chromosome 5
78.02 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:139150223-139186510 bp, + strand
From VEGA annotation of GRCm38

  36288 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41198  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Heatr2

Human
homologs
Human Homolog DNAAF5, dynein, axonemal, assembly factor 5
NCBI Gene ID 54919
neXtProt AC  NX_Q86Y56
Human Synonyms  CILD18, HEATR2
Human Chr (Location)  7p22.3; chr7:726701-786479 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human DNAAF5
Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(20) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Heatr2 interacts with 152 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process cilium movement, inner dynein arm assembly, ...
Component cytoplasm
Function dynein intermediate chain binding
Expression
cDNA source data(34)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(34) cDNA(34)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000025148 (Evidence)
Ensembl Gene ModelENSMUSG00000025857 (Evidence)
Entrez Gene433956 (Evidence)
UniGene5547
DFCITC1583661, TC1758260, TC1656972
DoTSDT.487663, DT.94240691
Consensus CDS ProjectCCDS39349.1
International Mouse Knockout Project StatusHeatr2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025148 VEGA Gene Model | MGI Sequence Detail 36288 C57BL/6J ±  kb
transcript OTTMUST00000061868 VEGA | MGI Sequence Detail 3450 Not Applicable 
polypeptide OTTMUSP00000030439 VEGA | MGI Sequence Detail 853 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(2) UniProt(6)
Polymorphisms
SNPs within 2kb(141 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011989 Armadillo-like helical
InterPro IPR016024 Armadillo-type fold
Protein Ontology PR:000029536 HEAT repeat-containing protein 2
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)
Other
accession IDs
MGI:2141278

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory