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Dnaaf5
Gene Detail
Symbol

Name
ID
Dnaaf5
dynein, axonemal, assembly factor 5
MGI:3616079
Synonyms
Heatr2
Feature Type
protein coding gene
Genetic Map
Chromosome 5
78.02 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:139150223-139186510 bp, + strand
From VEGA annotation of GRCm38

  36288 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41198  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DNAAF5
Gene Tree: Dnaaf5

Human
homologs
DNAAF5, dynein, axonemal, assembly factor 5
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 54919
neXtProt AC: NX_Q86Y56

Human Synonyms: CILD18, HEATR2

Human Chr (Location): 7p22.3; chr7:726701-786479 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human DNAAF5

Mutations,
alleles, and
phenotypes
All mutations/alleles(22) : Gene trapped(20) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Dnaaf5 interacts with 152 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process cell projection organization, cilium movement, ...
Component cytoplasm
Function dynein intermediate chain binding
Expression
cDNA source data(34)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dnaaf5    NEW 
Molecular
reagents
All nucleic(34) cDNA(34)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000025148 (Evidence)
Ensembl Gene Model ENSMUSG00000025857 (Evidence)
Entrez Gene 433956 (Evidence)
UniGene 5547
DFCI TC1583661, TC1656972, TC1758260
DoTS DT.487663, DT.94240691
Consensus CDS Project CCDS39349.1
International Mouse Phenotyping Consortium Status Dnaaf5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025148 VEGA Gene Model | MGI Sequence Detail 36288 C57BL/6J ±  kb
transcript OTTMUST00000061868 VEGA | MGI Sequence Detail 3450 Not Applicable 
polypeptide OTTMUSP00000030439 VEGA | MGI Sequence Detail 853 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(141 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011989 Armadillo-like helical
InterPro IPR016024 Armadillo-type fold
Protein Ontology PR:000029536 HEAT repeat-containing protein 2
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:215975 Diggle CP, et al., HEATR2 plays a conserved role in assembly of the ciliary motile apparatus. PLoS Genet. 2014 Sep;10(9):e1004577
All references(31)
Other
accession IDs
MGI:2141278

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory