Tg(KRT14-Kitl)1Takk
Transgene Detail

Summary

• Symbol: Tg(KRT14-Kitl)1Takk
• Name: transgene insertion 1, Takahiro Kunisada
• MGI ID: MGI:3607790
• Synonyms: K14-Scf, Kitl-Tg, KRT14-Kitl, SCF-Tg, TG1, Tg(KRT14-itl)1Takk
• Transgene: Tg(KRT14-Kitl)1Takk Location: unknown
• Alliance: Tg(KRT14-Kitl)1Takk page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-Kitl)1Takk expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Kitl (MGI:96974)

• The human cytokeratin 14 upstream region was used to drive expression of kit ligand. (J:49253)

Disease models

Tumor Data

List all tumor models in MMHCdb carrying Tg(KRT14-Kitl)1Takk

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

(C57BL x SJL) F1 fertilized oocytes were microinjected with the vector.

References

• Original: J:49253 Kunisada T, et al., Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation and migration of melanocyte precursors. Development. 1998 Aug;125(15):2915-23
• All: 16 reference(s)