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Ifi214 Gene Detail
Summary
  • Symbol
    Ifi214
  • Name
    interferon activated gene 214
  • Synonyms
    BC094916, Pyhin-B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3584522
    NCBI Gene: 545384
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:173348877-173363523 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 80.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    395 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3584522
 protein coding gene Chr1:173347283-173363523 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016811
 protein coding gene Chr1:179455761-179473698 (-)
A/J MGP_AJ_G0016790
 protein coding gene Chr1:172163253-172168368 (-)
AKR/J MGP_AKRJ_G0016755
 protein coding gene Chr1:177484757-177502702 (+)
BALB/cJ MGP_BALBcJ_G0016748
 protein coding gene Chr1:172678639-172695002 (-)
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0014919
 protein coding gene Chr1:163966629-163982883 (-)
CAST/EiJ MGP_CASTEiJ_G0016155
 protein coding gene Chr1:177414024-177431692 (+)
CBA/J MGP_CBAJ_G0016548
 protein coding gene Chr1:192190129-192199167 (+)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0016727
 protein coding gene Chr1:180672355-180689604 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016680
 protein coding gene Chr1:199286095-199323478 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017248
 protein coding gene Chr1:177235634-177245590 (-)
PWK/PhJ MGP_PWKPhJ_G0015941
 protein coding gene Chr1:170433278-170450683 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015723
 protein coding gene Chr1:176357515-176361777 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Synonyms
    IFNGIP1, PYHIN2
  • Links
    NCBI Gene ID: 3428
    neXtProt AC: NX_Q16666
    UniProt: Q16666

  • Chr Location
    1q23.1; chr1:158999968-159055155 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 545384 NCBI Gene Model | MGI Sequence Detail 14647 C57BL/6J ±  kb
transcript NM_001024721 RefSeq | MGI Sequence Detail 1294 C57BL/6  
polypeptide Q504N7 UniProt | EBI | MGI Sequence Detail 393 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:329937 Maltbaek JH, et al., ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP. Immunity. 2022 Oct 11;55(10):1799-1812.e4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory