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L1td1 Gene Detail
Summary
  • Symbol
    L1td1
  • Name
    LINE-1 type transposase domain containing 1
  • Synonyms
    ECAT11
  • Feature Type
    protein coding gene
  • IDs
    MGI:3578435
    NCBI Gene: 381591
  • Gene Overview
    MyGene.info: L1TD1
Location & Maps
more
  • Sequence Map
    Chr4:98726734-98738480 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11747 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 45.60 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    L1TD1, LINE-1 type transposase domain containing 1
  • Vertebrate Orthologs
    2
  • Human Ortholog
    L1TD1, LINE-1 type transposase domain containing 1
    Orthology source: HGNC
  • Synonyms
    ECAT11
  • Links
    NCBI Gene ID: 54596
    neXtProt AC: NX_Q5T7N2

  • Chr Location
    1p31.3; chr1:62194802-62212328 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
  • All Mutations and Alleles
    115
  • Chemically induced (other)
    2
  • Gene trapped
    110
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving L1td1
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit normal development and fertility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008672 VEGA Gene Model | MGI Sequence Detail 11747 C57BL/6J ±  kb
transcript OTTMUST00000096967 VEGA | MGI Sequence Detail 2547 Not Applicable  
polypeptide OTTMUSP00000054262 VEGA | MGI Sequence Detail 848 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    152 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000029596 LINE-1 type transposase domain-containing protein 1
  • InterPro Domains
    IPR004244 Transposase, L1
Molecular
Reagents
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  • All nucleic 39
    cDNA 37
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
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MGI:3034299, MGI:3034610
References
more
  • Summaries
    All 32
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 13
  • Earliest
    J:83420 Mitsui K, et al., The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell. 2003 May 30;113(5):631-42
  • Latest
    J:214809 Moniot B, et al., Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis. Development. 2014 Sep;141(18):3561-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory