inad
Gene Detail

Symbol Name ID

inad infantile neuroaxonal dystrophy MGI:3577064

Feature Type

heritable phenotypic marker

Genetic Map

Chromosome 1
Syntenic

Mapping data(1)

Alleles and phenotypes

All alleles(1) : Spontaneous(1)
 

Homozygous mutant mice die before sexual maturity and exhibit axonal dystrophic change appearing as spheroid bodies in the nervous system. Mice show progressive motor paralysis and atrophy of the hindlimbs.

 
Human Diseases Modeled Using Mouse inad (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(2)

References

(Earliest) J:97670 Matsushima Y, et al., A new mouse model for infantile neuroaxonal dystrophy, inad mouse, maps to mouse chromosome 1. Mamm Genome. 2005 Feb;16(2):73-8
All references(1)