Tg(CAG-cat,-lacZ)1Brn
Transgene Detail

Summary

• Symbol: Tg(CAG-cat,-lacZ)1Brn
• Name: transgene insertion 1, Anton Berns
• MGI ID: MGI:3044043
• Synonyms: ACZL, floxLacZ, FLZI, loxP-CAT/loxP-LacZ, Tg(ACTB-cat-lacZ)1Brn, Tg(CAG-cat-lacZ)1Brn
• Transgene: Tg(CAG-cat,-lacZ)1Brn Location: unknown
• Alliance: Tg(CAG-cat,-lacZ)1Brn page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene comprises the CMV enhancer and chicken beta-actin promoter and the beta-galactosidase coding sequence separated by the chloramphenicol acetyltransferase (cat) gene flanked by loxP sites. Beta-galactosidase expression is blocked by presence of the cat gene; when the CAT sequence is excised by Cre recombinase, beta-galactosidase is expressed. (J:66884, J:80158)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:80158 Akagi K, et al., Cre-mediated somatic site-specific recombination in mice. Nucleic Acids Res. 1997 May 1;25(9):1766-73
• All: 33 reference(s)