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Ighg2c Gene Detail
Summary
  • Symbol
    Ighg2c
  • Name
    immunoglobulin heavy constant gamma 2C
  • Feature Type
    gene segment
  • IDs
    MGI:2686979
    NCBI Gene: 404711
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:113287389-113288932 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 62.10 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686979
gene segment Chr12:113285325-113288932 (-)
129S1/SvImJ MGP_129S1SvImJ_G0000005
gene segment Chr12:115822114-115823632 (-)
A/J MGP_AJ_G0000005
gene segment Chr12:111311792-111317992 (-)
AKR/J MGP_AKRJ_G0000005
gene segment Chr12:114566280-114573076 (-)
BALB/cJ MGP_BALBcJ_G0000005
gene segment Chr12:111781904-111783530 (-)
C3H/HeJ MGP_C3HHeJ_G0000005
gene segment Chr12:115063518-115065144 (-)
C57BL/6NJ MGP_C57BL6NJ_G0000005
gene segment Chr12:119337741-119341348 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0000005
gene segment Chr12:123932299-123933925 (-)
DBA/2J MGP_DBA2J_G0000005
gene segment Chr12:110832288-110833918 (-)
FVB/NJ MGP_FVBNJ_G0000005
gene segment Chr12:109660784-109662408 (-)
LP/J MGP_LPJ_G0000005
gene segment Chr12:115634859-115636506 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0000005
gene segment Chr12:114070857-114072483 (-)
PWK/PhJ MGP_PWKPhJ_G0000006
gene segment Chr12:105508570-105510110 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0000006
gene segment Chr12:115032346-115033886 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 404711 NCBI Gene Model | MGI Sequence Detail 1544 C57BL/6J ±  kb
polypeptide F6TQW2 UniProt | EBI | MGI Sequence Detail 404 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
Molecular
Reagents
less
  • All nucleic 1
    Genomic 1
References
more
  • Summaries
    All 30
    Gene Ontology 7
  • Earliest
    J:5559 Taylor BA, et al., Genes for immunoglobulin heavy chain and serum prealbumin protein are linked in mouse. Nature. 1975 Aug 21;256(5519):644-6
  • Latest
    J:223449 Dosenovic P, et al., Slc15a4 function is required for intact class switch recombination to IgG2c in response to TLR9 stimulation. Immunol Cell Biol. 2015 Feb;93(2):136-46

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory