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Trim40 Gene Detail
Summary
  • Symbol
    Trim40
  • Name
    tripartite motif-containing 40
  • Synonyms
    LOC195359, LOC240093, LOC333872
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684881
    NCBI Gene: 195359
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:36881598-36890123 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 19.16 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684881
protein coding gene Chr17:36881596-36890157 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023685
protein coding gene Chr17:37232478-37241029 (-)
A/J MGP_AJ_G0023643
protein coding gene Chr17:36061344-36069857 (-)
AKR/J MGP_AKRJ_G0023614
protein coding gene Chr17:36495514-36504051 (-)
BALB/cJ MGP_BALBcJ_G0023650
protein coding gene Chr17:36301976-36310537 (-)
C3H/HeJ MGP_C3HHeJ_G0023412
protein coding gene Chr17:37009228-37018136 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024088
protein coding gene Chr17:38830353-38838937 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021556
protein coding gene Chr17:33876292-33884763 (-)
CAST/EiJ MGP_CASTEiJ_G0022897
protein coding gene Chr17:37137453-37146016 (-)
CBA/J MGP_CBAJ_G0023389
protein coding gene Chr17:40345321-40353873 (-)
DBA/2J MGP_DBA2J_G0023514
protein coding gene Chr17:35453259-35461750 (-)
FVB/NJ MGP_FVBNJ_G0023487
protein coding gene Chr17:35062607-35071120 (-)
LP/J MGP_LPJ_G0023592
protein coding gene Chr17:37764857-37773378 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023510
protein coding gene Chr17:39142311-39150824 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024133
protein coding gene Chr17:36834394-36843733 (-)
PWK/PhJ MGP_PWKPhJ_G0022649
protein coding gene Chr17:34230471-34239356 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022468
protein coding gene Chr17:34916234-34926362 (-)
WSB/EiJ MGP_WSBEiJ_G0022964
protein coding gene Chr17:37148679-37157179 (-)



Homology
more
  • Human Ortholog
    TRIM40, tripartite motif containing 40
  • Vertebrate Orthologs
    6
  • Human Ortholog
    TRIM40, tripartite motif containing 40
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RNF35
  • Links
    NCBI Gene ID: 135644
    neXtProt AC: NX_Q6P9F5
    UniProt: Q6P9F5

  • Chr Location
    6p22.1; chr6:30135998-30148773 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073399 Ensembl Gene Model | MGI Sequence Detail 8526 C57BL/6J ±  kb
transcript ENSMUST00000087158 Ensembl | MGI Sequence Detail 2117 Not Applicable  
polypeptide ENSMUSP00000084400 Ensembl | MGI Sequence Detail 246 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
Other
Accession IDs
less
MGI:2685165, MGI:2685711
References
more
  • Summaries
    All 23
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:255265 Zhao C, et al., The E3 Ubiquitin Ligase TRIM40 Attenuates Antiviral Immune Responses by Targeting MDA5 and RIG-I. Cell Rep. 2017 Nov 7;21(6):1613-1623

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/05/2019
MGI 6.14
The Jackson Laboratory