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Qrfpr
Gene Detail
Symbol

Name
ID
Qrfpr
pyroglutamylated RFamide peptide receptor
MGI:2677633
Synonyms
AQ27, Gpr103
Feature Type
protein coding gene
Genetic Map
Chromosome 3
17.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr3:36179427-36222275 bp, - strand
From Ensembl annotation of GRCm38

  42849 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18865  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: QRFPR
Protein SuperFamily: orexigenic neuropeptide QRFP receptor
Gene Tree: Qrfpr

Human
homologs
QRFPR, pyroglutamylated RFamide peptide receptor
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 84109
neXtProt AC: NX_Q96P65

Human Synonyms: AQ27, GPR103, SP9155

Human Chr (Location): 4q27; chr4:121327211-121381059 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a mutation diisplay kyphosis with abnormal vertebrae morphology and development including osteopenia of the vertebrae.
 
Interactions
Qrfpr interacts with 139 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Expression
cDNA source data(7)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase qrfpr    NEW 
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000058400 (Evidence)
Entrez Gene 229214 (Evidence)
UniGene 330975
DFCI TC1587412
DoTS DT.101721650, DT.91584697
NIA Mouse Gene Index U056803
Consensus CDS Project CCDS17311.1
International Mouse Phenotyping Consortium Status Qrfpr
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000058400 Ensembl Gene Model | MGI Sequence Detail 42849 C57BL/6J ±  kb
transcript ENSMUST00000091227 Ensembl | MGI Sequence Detail 1800 Not Applicable 
polypeptide ENSMUSP00000088768 Ensembl | MGI Sequence Detail 433 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(4)
Polymorphisms
SNPs within 2kb(318 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR000611 Neuropeptide Y receptor family
Protein Ontology PR:000001498 orexigenic neuropeptide QRFP receptor
References
(Earliest) J:84528 Jiang Y, et al., Identification and characterization of a novel RF-amide peptide ligand for orphan G-protein-coupled receptor SP9155. J Biol Chem. 2003 Jul 25;278(30):27652-7
(Latest) J:204140 Loktev AV, et al., Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia. Cell Rep. 2013 Dec 12;5(5):1316-29
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory