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Qrfpr
Gene Detail
Symbol

Name
ID
Qrfpr
pyroglutamylated RFamide peptide receptor
MGI:2677633
Synonyms
AQ27, Gpr103
Feature Type
protein coding gene
Genetic Map
Chromosome 3
17.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr3:36179424-36222275 bp, - strand
From VEGA annotation of GRCm38

  42852 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18865  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: orexigenic neuropeptide QRFP receptor
Gene Tree: Qrfpr

Human
homologs
Human Homolog QRFPR, pyroglutamylated RFamide peptide receptor
NCBI Gene ID 84109
neXtProt AC  NX_Q96P65
Human Synonyms  AQ27, GPR103, SP9155
Human Chr (Location)  4q27; chr4:121328642-121381026 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a mutation diisplay kyphosis with abnormal vertebrae morphology and development including osteopenia of the vertebrae.
 
Interactions
Qrfpr interacts with 140 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Expression
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000026506 (Evidence)
Ensembl Gene ModelENSMUSG00000058400 (Evidence)
Entrez Gene229214 (Evidence)
UniGene330975
DFCITC1587412
DoTSDT.101721650, DT.91584697
NIA Mouse Gene IndexU056803
Consensus CDS ProjectCCDS17311.1
International Mouse Knockout Project StatusQrfpr
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026506 VEGA Gene Model | MGI Sequence Detail 42852 C57BL/6J ±  kb
transcript OTTMUST00000065566 VEGA | MGI Sequence Detail 1803 Not Applicable 
polypeptide OTTMUSP00000032687 VEGA | MGI Sequence Detail 433 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(2) UniProt(9)
Polymorphisms
SNPs within 2kb(318 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR000611 Neuropeptide Y receptor family
Protein Ontology PR:000001498 orexigenic neuropeptide QRFP receptor
References
(Earliest) J:84528 Jiang Y, et al., Identification and characterization of a novel RF-amide peptide ligand for orphan G-protein-coupled receptor SP9155. J Biol Chem. 2003 Jul 25;278(30):27652-7
(Latest) J:204140 Loktev AV, et al., Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia. Cell Rep. 2013 Dec 12;5(5):1316-29
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory