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Mir122a
Gene Detail
 Symbol
Name
ID
Mir122a
microRNA 122a
MGI:2676805
BioType Conflict
Synonyms Mirn122a, mmu-mir-122, mmu-mir-122a
Feature Type miRNA gene
Genetic Map
Chromosome 18
38.39 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr18:65248861-65248926 bp, + strand
From miRBase annotation of GRCm38

  66 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
Gene Tree: Mir122a
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
 
Mice homozygous for a knock-out allele exhibit steatohepatitis with fibrosis and hepatocellular carcinoma.
 
Phenotype Images(9)
Interactions
Mir122a interacts with 2812 markers (0610011F06Rik, 0610037L13Rik, 1110002E22Rik, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process BMP signaling pathway, cellular response to amino acid stimulus, ...
Expression
Literature Summary: (11 records)
Data Summary: Results (5)    Tissues (5)    Images (1)
Theiler Stages: 15, 17, 19, 28
Assay TypeResults
RNA in situ 2
RT-PCR 3
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(3) Primer pair(1) Other(2)
Other database
links
Ensembl Gene ModelENSMUSG00000065402 (Evidence)
Entrez Gene387231 (Evidence)
miRBaseMI0000256
International Mouse Knockout Project StatusMir122a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 387231 NCBI Gene Model | MGI Sequence Detail 66 C57BL/6J ±  kb
transcript NR_029600 RefSeq | MGI Sequence Detail 66 C57BL/6 

For the selected sequences
All sequences(6) RefSeq(1)
Polymorphisms SNPs within 2kb(45 from dbSNP Build 137)
References (Earliest) J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
(Latest) J:205607 Hsu SH, et al., Hepatic loss of miR-122 predisposes mice to hepatobiliary cyst and hepatocellular carcinoma upon diethylnitrosamine exposure. Am J Pathol. 2013 Dec;183(6):1719-30
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory