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L3mbtl1
Gene Detail
Symbol

Name
ID
L3mbtl1
l(3)mbt-like (Drosophila)
MGI:2676663
Synonyms
L3MBTL1
Feature Type
protein coding gene
Genetic Map
Chromosome 2
83.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:162943472-162974522 bp, + strand
From VEGA annotation of GRCm38

  31051 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41846  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: L3mbtl1

Human
homologs
Human Homolog L3MBTL1, l(3)mbt-like 1 (Drosophila)
NCBI Gene ID 26013
neXtProt AC  NX_Q9Y468
Human Synonyms  dJ138B7.3, H-L(3)MBT, L3MBTL, ZC2HC3
Human Chr (Location)  20q13.12; chr20:43507680-43541895 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(2) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit normal nervous system phenotype, hematopoietic system phenotype, immune system phenotype, cellular phenotype, and lifespan.
 
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process chromatin modification, negative regulation of transcription, DNA-templated, ...
Component chromatin, condensed chromosome, ...
Function chromatin binding, histone binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (205)    Tissues (135)    Images (34)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 205
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(5) Primer pair(1)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000001061 (Evidence)
Ensembl Gene ModelENSMUSG00000035576 (Evidence)
Entrez Gene241764 (Evidence)
UniGene187086
DFCITC1603820, TC1615673
DoTSDT.101122229, DT.110674886, DT.110674891, DT.110674899, DT.110674900, DT.91392665
NIA Mouse Gene IndexU002776
Consensus CDS ProjectCCDS38314.1
International Mouse Knockout Project StatusL3mbtl1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001061 VEGA Gene Model | MGI Sequence Detail 31051 C57BL/6J ±  kb
transcript OTTMUST00000002105 VEGA | MGI Sequence Detail 2724 Not Applicable 
polypeptide OTTMUSP00000001015 VEGA | MGI Sequence Detail 826 Not Applicable 

For the selected sequences
All sequences(71) RefSeq(23) UniProt(8)
Polymorphisms
SNPs within 2kb(211 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004092 Mbt repeat
InterPro IPR001660 Sterile alpha motif domain
InterPro IPR013761 Sterile alpha motif/pointed domain
InterPro IPR021129 Sterile alpha motif, type 1
InterPro IPR002515 Zinc finger, C2HC-type
Protein Ontology PR:000009640 lethal(3)malignant brain tumor-like protein 1
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory