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Wapal
Gene Detail
Symbol

Name
ID
Wapal
wings apart-like homolog (Drosophila)
MGI:2675859
Synonyms
A530089A20Rik, mKIAA0261
Feature Type
protein coding gene
Genetic Map
Chromosome 14
20.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:34673928-34747983 bp, + strand
From VEGA annotation of GRCm38

  74056 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41002  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: WAPAL
Gene Tree: Wapal

Human
homologs
WAPAL, wings apart-like homolog (Drosophila)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 23063
neXtProt AC: NX_Q7Z5K2

Human Synonyms: FOE, KIAA0261, WAPL

Human Chr (Location): 10q23.2; chr10:86435256-86521816 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(135) : Gene trapped(133) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a targeted allele exhibit prenatal lethality.
 
Interactions
Wapal interacts with 414 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process cell cycle, cell division, ...
Component chromatin, chromosome, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(13)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase wapal    NEW 
Molecular
reagents
All nucleic(14) cDNA(14)
Microarray probesets(9)
Other database
links
VEGA Gene Model OTTMUSG00000024463 (Evidence)
Ensembl Gene Model ENSMUSG00000041408 (Evidence)
Entrez Gene 218914 (Evidence)
DFCI TC1607505, TC1578487, TC1628775, TC1693368, TC1614136, TC1658906
DoTS DT.99854446, DT.490967, DT.110759207, DT.102547847, DT.491225, DT.94144934, DT.532630, DT.532629
Consensus CDS Project CCDS36880.1
International Mouse Phenotyping Consortium Status Wapal
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024463 VEGA Gene Model | MGI Sequence Detail 74056 C57BL/6J ±  kb
transcript OTTMUST00000059998 VEGA | MGI Sequence Detail 6351 Not Applicable 
polypeptide OTTMUSP00000029240 VEGA | MGI Sequence Detail 1200 Not Applicable 

For the selected sequences
All sequences(76) RefSeq(6) UniProt(4)
Polymorphisms
SNPs within 2kb(222 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR012502 Wings apart-like, metazoan/plants
InterPro IPR022771 Wings apart-like protein
Protein Ontology PR:000017368 wings apart-like protein
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:205429 Tedeschi A, et al., Wapl is an essential regulator of chromatin structure and chromosome segregation. Nature. 2013 Sep 26;501(7468):564-8
All references(33)
Other
accession IDs
MGI:2443602

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory