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Klre1 Gene Detail
Summary
  • Symbol
    Klre1
  • Name
    killer cell lectin-like receptor family E member 1
  • Synonyms
    Klre-1, NKG2I
  • Feature Type
    protein coding gene
  • IDs
    MGI:2662547
    NCBI Gene: 243655
Location & Maps
more
  • Sequence Map
    Chr6:129577905-129585827 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7923 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 63.41 cM
  • Mapping Data
    1 experiment
Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice are viable and fertile and display impaired natural killer cell mediated allogeneic cytotoxicity.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000056473 VEGA Gene Model | MGI Sequence Detail 7923 C57BL/6J ±  kb
transcript OTTMUST00000139499 VEGA | MGI Sequence Detail 1294 Not Applicable  
polypeptide OTTMUSP00000073187 VEGA | MGI Sequence Detail 226 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    196 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 3
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 22
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:83529 Wilhelm BT, et al., Identification of a new murine lectin-like gene in close proximity to CD94. Immunogenetics. 2003 Apr;55(1):53-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory