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Klre1
Gene Detail
Symbol

Name
ID
Klre1
killer cell lectin-like receptor family E member 1
MGI:2662547
Synonyms
Klre-1, NKG2I
Feature Type
protein coding gene
Genetic Map
Chromosome 6
63.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:129577893-129585824 bp, + strand
From Ensembl annotation of GRCm38

  7932 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:17794  Vertebrate Homology Class
1 mouse; 1 rat; 1 cattle

Protein SuperFamily: natural killer cell receptor CD94/NKG2
Gene Tree: Klre1

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice are viable and fertile and display impaired natural killer cell mediated allogeneic cytotoxicity.
 
Interactions
Klre1 interacts with 27 markers (Mir23a, Mir23b, Mir103-1, ...)
Expression
cDNA source data(3)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(3) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000050241 (Evidence)
Entrez Gene243655 (Evidence)
UniGene30968
DFCITC1612575, TC1589786
DoTSDT.94192712, DT.91380324
Consensus CDS ProjectCCDS20589.1
International Mouse Knockout Project StatusKlre1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050241 Ensembl Gene Model | MGI Sequence Detail 7932 C57BL/6J ±  kb
transcript ENSMUST00000053708 Ensembl | MGI Sequence Detail 1303 Not Applicable 
polypeptide ENSMUSP00000055779 Ensembl | MGI Sequence Detail 226 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(20) UniProt(4)
Polymorphisms
SNPs within 2kb(126 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001304 C-type lectin
InterPro IPR016187 C-type lectin fold
InterPro IPR016186 C-type lectin-like
References
(Earliest) J:83529 Wilhelm BT, et al., Identification of a new murine lectin-like gene in close proximity to CD94. Immunogenetics. 2003 Apr;55(1):53-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(24)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory