Tg(F3)1Nmk
Transgene Detail

Summary

• Symbol: Tg(F3)1Nmk
• Name: transgene insertion 1, Nigel Mackman
• MGI ID: MGI:2654474
• Synonyms: hF3⁺, hTF, hTF⁺
• Transgene: Tg(F3)1Nmk Location: unknown
• Alliance: Tg(F3)1Nmk page

Transgene origin

• Strain of Origin: C57BL/6 x BALB/c

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(F3)1Nmk expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  F3 (2152)

  F3	(MGI:88381)

• Mutation details: A human F3 cDNA minigene was used for the transgene, including the promoter and intron 1. Transgene expression was confirmed in brain, lung, kidney, heart, spleen, and liver by Northern blot and RT-PCR analysis. Transgene expression was determined to be 1% that of endogenous mouse F3 expression. (J:82528)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

9 founders were created. The founders each carry 1 copy of the transgene

References

• Original: J:82528 Parry GC, et al., Low levels of tissue factor are compatible with development and hemostasis in mice. J Clin Invest. 1998 Feb 1;101(3):560-9
• All: 31 reference(s)