H4c17 MGI Mouse Gene Detail - MGI:2448441

Symbol

H4c17
Name

H4 clustered histone 17
Synonyms

Gm11275, Hist1h4m

Feature Type

protein coding gene
IDs

MGI:2448441
NCBI Gene: 100041230
Member of

Hist1 cluster
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr13:21995916-21996317 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 7.99 cM, cytoband A2-A3
Mapping Data

1 experiment

Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2448441	protein coding gene	Chr13:21995916-21996320 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020303	protein coding gene	Chr13:19129040-19131254 (-)
A/J	MGP_AJ_G0020260	protein coding gene	Chr13:18696450-18696851 (-)
AKR/J	MGP_AKRJ_G0020232	protein coding gene	Chr13:18986088-18986489 (+)
BALB/cJ	MGP_BALBcJ_G0020247	protein coding gene	Chr13:18746243-18746644 (-)
C3H/HeJ	MGP_C3HHeJ_G0020057	protein coding gene	Chr13:19112563-19112964 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0020686	protein coding gene	Chr13:19803198-19803590 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018299	protein coding gene	Chr13:17206896-17207290 (-)
CAST/EiJ	MGP_CASTEiJ_G0019586	protein coding gene	Chr13:19135046-19135444 (-)
CBA/J	MGP_CBAJ_G0020011	protein coding gene	Chr13:20468566-20471338 (-)
DBA/2J	MGP_DBA2J_G0020134	protein coding gene	Chr13:18340334-18340735 (-)
FVB/NJ	MGP_FVBNJ_G0020121	protein coding gene	Chr13:17980176-17980577 (-)
LP/J	MGP_LPJ_G0020204	protein coding gene	Chr13:19353278-19353679 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020157	protein coding gene	Chr13:21105931-21106310 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020720	protein coding gene	Chr13:18804788-18805189 (+)
PWK/PhJ	MGP_PWKPhJ_G0019342	protein coding gene	Chr13:18575617-18576233 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0019154	protein coding gene	Chr13:18039664-18040005 (-)
WSB/EiJ	MGP_WSBEiJ_G0019646	protein coding gene	Chr13:19164898-19165296 (-)

Human Ortholog

H4C4, H4 clustered histone 4

Vertebrate Orthologs

16

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

H4C4, H4 clustered histone 4
Synonyms

dJ221C16.9, H4-16, H4/b, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C3, H4C5, H4C6, H4C8, H4C9, H4FB, HIST1H4D
Links

HGNC:4782

NCBI Gene ID: 8360

neXtProt AC: NX_P62805

UniProt: P62805
Chr Location

6p22.2; chr6:26188710-26189112 (-) GRCh38

Human Ortholog

H4C5, H4 clustered histone 5
Synonyms

H4-16, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C3, H4C4, H4C6, H4C8, H4C9, H4FJ, H4/j, HIST1H4E, TEBIVANED3, TEVANED3
Links

HGNC:4790

NCBI Gene ID: 8367

neXtProt AC: NX_P62805

UniProt: P62805
Chr Location

6p22.2; chr6:26204610-26205021 (+) GRCh38

MGI Vertebrate Homology

H4c17 stringent orthology
2 human;1 mouse;4 rat;10 zebrafish
HCOP

vertebrate homology predictions: H4C4, H4C5
Gene Tree

H4c17

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Phenotype Summary

8 phenotype references

All Mutations and Alleles

2
Chemically induced (other)

1
Radiation induced

1
Genomic Mutations

2 involving H4c17
Find Mice (IMSR)

2 strains or lines available

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All GO Annotations

4
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

737
Tissues

23
cDNA Data

2
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

32
RefSeq

2
UniProt

1
CCDS

CCDS56872.1

Ensembl

ENSMUSG00000069306 (Evidence)
NCBI Gene

100041230

			Length	Strain/Species	Flank
genomic	ENSMUSG00000069306	Ensembl Gene Model \| MGI Sequence Detail	402	C57BL/6J	± kb
transcript	ENSMUST00000104941	Ensembl \| MGI Sequence Detail	402	Not Applicable
polypeptide	ENSMUSP00000100546	Ensembl \| MGI Sequence Detail	103	Not Applicable

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UniProt

1 Sequence

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All nucleic 4

Genomic 1

cDNA 2

Primer pair 1

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MGI:3711960

Summaries

All 24

Developmental Gene Expression 1

Gene Ontology 1

Phenotypes 8
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:175731 Liu LJ, et al., Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development. Gene. 2011 Sep 1;483(1-2):1-10

TSS for H4c17:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr118796	Chr13:21995907-21995924 (+)	0 bp
Tssr118797	Chr13:21995930-21995936 (+)	17 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23