About   Help   FAQ
H3c14 Gene Detail
Summary
  • Symbol
    H3c14
  • Name
    H3 clustered histone 14
  • Synonyms
    H3-615, H3f2, Hist2h3c1, Hist2h3ca1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448355
    NCBI Gene: 15077
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:96154001-96154664 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 41.69 cM, cytoband F1-F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3 from dbSNP Build 142
  • Strain Annotations
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448355
protein coding gene Chr3:96154001-96155825 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0026768
protein coding gene Chr3:95812557-95815558 (+)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from multigenic genotypes
    5 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving H3c14
  • Find Mice (IMSR)
A homozygous point mutation causes microphthalmia (resulting from abnormal cornea, lens and retina development), increased locomotor activity, rearing and body temperature, and decreased anxiety, body mass and blood lipid levels.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 15077 NCBI Gene Model | MGI Sequence Detail 664 C57BL/6J ±  kb
transcript NM_178216 RefSeq | MGI Sequence Detail 664 C57BL/6  
polypeptide P84228 UniProt | EBI | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 4
Other
Accession IDs
less
MGI:1194885, MGI:3035157
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:7225 Sittman DB, et al., Structure of a cluster of mouse histone genes. Nucleic Acids Res. 1983 Oct 11;11(19):6679-97
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/07/2021
MGI 6.17
The Jackson Laboratory