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Kcnh8
Gene Detail
 Symbol
Name
ID
Kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
MGI:2445160
Synonyms C130090D05Rik, ELK1, Kv12.1
Feature Type protein coding gene
Genetic Map
Chromosome 17
27.37 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr17:52602709-52979194 bp, + strand
From VEGA annotation of GRCm38

  376486 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14332  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: potassium voltage-gated channel, subfamily H
Gene Tree: Kcnh8

Human
homologs
Human Homolog KCNH8, potassium voltage-gated channel, subfamily H (eag-related), member 8
NCBI Gene ID 131096
neXtProt AC  NX_Q96L42
Human Synonyms  ELK, ELK1, elk3, Kv12.1
Human Chr (Location)  3p24.3; chr3:19148454-19535643 (+)  GRCh38
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process ion transport, negative regulation of apoptotic process, ...
Component integral component of membrane, integral component of plasma membrane, ...
Function ion channel activity, phosphorelay sensor kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (3)    Tissues (2)   
Theiler Stages: 25, 28
Assay TypeResults
RT-PCR 3
cDNA source data(3)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(4) cDNA(3) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000044933 (Evidence)
Ensembl Gene ModelENSMUSG00000035580 (Evidence)
Entrez Gene211468 (Evidence)
DFCITC1588145, TC1650221
DoTSDT.101345250, DT.55109344, DT.91555279
NIA Mouse Gene IndexU018100, U288468
Consensus CDS ProjectCCDS57101.1
International Mouse Knockout Project StatusKcnh8
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000044933 VEGA Gene Model | MGI Sequence Detail 376486 C57BL/6J ±  kb
transcript OTTMUST00000118100 VEGA | MGI Sequence Detail 4287 Not Applicable 
polypeptide OTTMUSP00000065953 VEGA | MGI Sequence Detail 1102 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(4) UniProt(4)
Polymorphisms SNPs within 2kb(2307 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000595 Cyclic nucleotide-binding domain
InterPro IPR018490 Cyclic nucleotide-binding-like
InterPro IPR005821 Ion transport domain
InterPro IPR001610 PAC motif
InterPro IPR000700 PAS-associated, C-terminal
InterPro IPR000014 PAS domain
InterPro IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERG
InterPro IPR003950 Potassium channel, voltage-dependent, ELK
InterPro IPR014710 RmlC-like jelly roll fold
Protein Ontology PR:000000797 voltage-gated potassium channel KCNH8
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:154739 Quina LA, et al., Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22
All references(25)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory