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Xylt2
Gene Detail
Symbol

Name
ID
Xylt2
xylosyltransferase II
MGI:2444797
Synonyms
E030002B02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
58.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:94663851-94677515 bp, - strand
From VEGA annotation of GRCm38

  13665 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23349  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: XYLT2
Gene Tree: Xylt2

Human
homologs
XYLT2, xylosyltransferase II
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 64132
neXtProt AC: NX_Q9H1B5

Human Synonyms: PXYLT2, XT2, XT-II, xylT-II

Human Chr (Location): 17q21.33; chr17:50346032-50361185 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human XYLT2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Genomic Mutations involving Xylt2 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele lack most liver proteoglycans and develop many aspects of polycystic liver and kidney disease, including biliary tract hyperplasia, liver fibrosis, biliary cysts, renal tubule dilation, basement membrane abnormalities and hydronephrosis.
 
Phenotype Images(5)
Interactions
Xylt2 interacts with 126 markers (Mir18, Mir18b, Mir23b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (124)    Tissues (97)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 124
cDNA source data(111)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase xylt2    NEW 
Molecular
reagents
All nucleic(111) cDNA(111)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000002014 (Evidence)
Ensembl Gene Model ENSMUSG00000020868 (Evidence)
Entrez Gene 217119 (Evidence)
UniGene 100638
DFCI TC1575053
DoTS DT.101380454, DT.101726053
NIA Mouse Gene Index U033289
EC 2.4.2.26
Consensus CDS Project CCDS48888.1
International Mouse Phenotyping Consortium Status Xylt2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000002014 VEGA Gene Model | MGI Sequence Detail 13665 C57BL/6J ±  kb
transcript OTTMUST00000004063 VEGA | MGI Sequence Detail 3442 Not Applicable 
polypeptide OTTMUSP00000001954 VEGA | MGI Sequence Detail 865 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(10) UniProt(7)
Polymorphisms
SNPs within 2kb(115 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003406 Glycosyl transferase, family 14
InterPro IPR024448 Xylosyltransferase
Protein Ontology PR:000017516 xylosyltransferase 2
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory