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Scara3 Gene Detail
Summary
  • Symbol
    Scara3
  • Name
    scavenger receptor class A, member 3
  • Synonyms
    C130058N24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444418
    NCBI Gene: 219151
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:65919394-65953930 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 34.36 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    168 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444418
protein coding gene Chr14:65919394-65953935 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021487
protein coding gene Chr14:60559570-60596057 (-)
A/J MGP_AJ_G0021446
protein coding gene Chr14:59143563-59177868 (-)
AKR/J MGP_AKRJ_G0021422
protein coding gene Chr14:61196347-61230688 (-)
BALB/cJ MGP_BALBcJ_G0021452
protein coding gene Chr14:59084905-59119640 (-)
C3H/HeJ MGP_C3HHeJ_G0021229
protein coding gene Chr14:60872801-60908327 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021891
protein coding gene Chr14:63353144-63388277 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019431
protein coding gene Chr14:57065034-57097893 (-)
CAST/EiJ MGP_CASTEiJ_G0020746
protein coding gene Chr14:57309351-57386331 (-)
CBA/J MGP_CBAJ_G0021196
protein coding gene Chr14:65269358-65305216 (-)
DBA/2J MGP_DBA2J_G0021319
protein coding gene Chr14:58790505-58824861 (-)
FVB/NJ MGP_FVBNJ_G0021298
protein coding gene Chr14:58200493-58234742 (-)
LP/J MGP_LPJ_G0021394
protein coding gene Chr14:61601575-61635934 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021327
protein coding gene Chr14:64347259-64381472 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021914
protein coding gene Chr14:60397208-60431526 (-)
PWK/PhJ MGP_PWKPhJ_G0020490
protein coding gene Chr14:55484807-55553557 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020323
protein coding gene Chr14:56349637-56399216 (-)
WSB/EiJ MGP_WSBEiJ_G0020799
protein coding gene Chr14:60688585-60723539 (-)



Homology
more
  • Human Ortholog
    SCARA3, scavenger receptor class A member 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SCARA3, scavenger receptor class A member 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    APC7, CSR, CSR1, MSLR1, MSRL1
  • Links
    NCBI Gene ID: 51435
    neXtProt AC: NX_Q6AZY7
    UniProt: Q6AZY7

  • Chr Location
    8p21.1; chr8:27633665-27734027 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9437
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SCARA3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 219151 NCBI Gene Model | MGI Sequence Detail 34537 C57BL/6J ±  kb
transcript NM_172604 RefSeq | MGI Sequence Detail 3405 C57BL/6  
polypeptide Q8C850 UniProt | EBI | MGI Sequence Detail 606 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    cDNA 34

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 9
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:235644 Wu Y, et al., Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury. PLoS Genet. 2016 Sep;12(9):e1006355

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/11/2018
MGI 6.13
The Jackson Laboratory