About   Help   FAQ
G2e3
Gene Detail
 Symbol
Name
ID
G2e3
G2/M-phase specific E3 ubiquitin ligase
MGI:2444298
Synonyms 6030408C04Rik, D930034K21Rik, mKIAA1333
Feature Type protein coding gene
Genetic Map
Chromosome 12
22.11 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:51348061-51376986 bp, + strand
From VEGA annotation of GRCm38

  28926 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32362  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: G2e3

Human
homologs
Human Homolog G2E3, G2/M-phase specific E3 ubiquitin protein ligase
NCBI Gene ID 55632
neXtProt AC  NX_Q7L622
Human Synonyms  KIAA1333, PHF7B
Human Chr (Location)  14q12; chr14:30559123-30619840 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(34) : Gene trapped(34)
Incidental mutations (data from Mutagenetix , APF )
 
Embryos homozygous for a gene trap allele that inactivates this gene die prior to implantation due to massive apoptosis which results in involution of the blastocyst.
 
Interactions
G2e3 interacts with 398 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process apoptotic process, blastocyst development, ...
Component cytoplasm, nucleus
Function coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (78)    Tissues (67)    Images (22)
Theiler Stages: 17, 19, 20, 22, 24, 28
Assay TypeResults
RNA in situ 34
In situ reporter (knock in) 40
RT-PCR 4
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(15) Primer pair(1)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000031423 (Evidence)
Ensembl Gene ModelENSMUSG00000035293 (Evidence)
Entrez Gene217558 (Evidence)
DFCITC1579802, TC1603003, TC1615264, TC1646776, TC1690927, TC1756790
DoTSDT.101279221, DT.488555, DT.522220, DT.94267378
NIA Mouse Gene IndexU043274
EC6.3.2.-
Consensus CDS ProjectCCDS25900.1, CCDS49061.1, CCDS49062.1
International Mouse Knockout Project StatusG2e3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031423 VEGA Gene Model | MGI Sequence Detail 28926 C57BL/6J ±  kb
transcript OTTMUST00000077856 VEGA | MGI Sequence Detail 2926 Not Applicable 
polypeptide OTTMUSP00000041271 VEGA | MGI Sequence Detail 739 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(6) UniProt(4)
Polymorphisms SNPs within 2kb(343 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000569 HECT
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
Protein Ontology PR:000007742 G2/M phase-specific E3 ubiquitin-protein ligase
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)
Other
accession IDs
MGI:2144993, MGI:2444867

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory