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Srcap Gene Detail
Summary
  • Symbol
    Srcap
  • Name
    Snf2-related CREBBP activator protein
  • Synonyms
    B930091H02Rik, D030022P06Rik, F630004O05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444036
    NCBI Gene: 100043597
  • Gene Overview
    MyGene.info: SRCAP
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:127511983-127561219 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 69.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    121 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444036
protein coding gene Chr7:127511983-127561219 (.)
129S1/SvImJ MGP_129S1SvImJ_G0033041
protein coding gene Chr7:131864525-131920187 (+)
A/J MGP_AJ_G0033024
protein coding gene Chr7:128363640-128413267 (+)
AKR/J MGP_AKRJ_G0032956
protein coding gene Chr7:131665279-131718161 (+)
BALB/cJ MGP_BALBcJ_G0033025
protein coding gene Chr7:128009956-128059744 (+)
C3H/HeJ MGP_C3HHeJ_G0032739
protein coding gene Chr7:131568993-131620035 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033534
protein coding gene Chr7:137010852-137062962 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030507
protein coding gene Chr7:129554079-129601024 (+)
CAST/EiJ MGP_CASTEiJ_G0032068
protein coding gene Chr7:123363455-123415996 (+)
CBA/J MGP_CBAJ_G0032712
protein coding gene Chr7:141636207-141691243 (+)
DBA/2J MGP_DBA2J_G0032864
protein coding gene Chr7:126336991-126387046 (+)
FVB/NJ MGP_FVBNJ_G0032817
protein coding gene Chr7:126182715-126232704 (+)
LP/J MGP_LPJ_G0032958
protein coding gene Chr7:133347505-133398643 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032849
protein coding gene Chr7:142750240-142809279 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033554
protein coding gene Chr7:130655070-130713738 (+)
PWK/PhJ MGP_PWKPhJ_G0031775
protein coding gene Chr7:119345713-119396263 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031621
protein coding gene Chr7:117471115-117521924 (+)
WSB/EiJ MGP_WSBEiJ_G0032180
protein coding gene Chr7:131629326-131680467 (+)



Homology
more
  • Human Ortholog
    SRCAP, Snf2 related CREBBP activator protein
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SRCAP, Snf2 related CREBBP activator protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    DOMO1, EAF1, FLHS, SWR1
  • Links
    NCBI Gene ID: 10847
    neXtProt AC: NX_Q6ZRS2
    UniProt: Q6ZRS2

  • Chr Location
    16p11.2; chr16:30699141-30740129 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 100043597 NCBI Gene Model | MGI Sequence Detail 49237 C57BL/6J ±  kb
transcript NM_001304266 RefSeq | MGI Sequence Detail 10914 C57BL/6  
polypeptide NP_001291195 RefSeq | MGI Sequence Detail 3271 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    12 Sequences
  • InterPro Domains
    IPR017956 AT hook, DNA-binding motif
    IPR001650 Helicase, C-terminal
    IPR014012 Helicase/SANT-associated domain
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR038718 SNF2-like, N-terminal domain superfamily
    IPR000330 SNF2-related, N-terminal domain
Molecular
Reagents
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  • All nucleic 29
    Genomic 1
    cDNA 26
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:2445189, MGI:3603830
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory