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Srcap Gene Detail
Summary
  • Symbol
    Srcap
  • Name
    Snf2-related CREBBP activator protein
  • Synonyms
    B930091H02Rik, D030022P06Rik, F630004O05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444036
    NCBI Gene: 100043597
  • Gene Overview
    MyGene.info: SRCAP
Location & Maps
more
  • Sequence Map
    Chr7:127511983-127561219 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      49237 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SRCAP, Snf2-related CREBBP activator protein
  • Vertebrate Orthologs
    7
  • Human Ortholog
    SRCAP, Snf2-related CREBBP activator protein
    Orthology source: HomoloGene
  • Synonyms
    DOMO1, EAF1, FLHS, SWR1
  • Links
    NCBI Gene ID: 10847
    neXtProt AC: NX_Q6ZRS2

  • Chr Location
    16p11.2; chr16:30699141-30740129 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human SRCAP associations

Human Disease Mouse Models
       Floating-Harbor Syndrome; FLHS   OMIM: 136140
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    68
  • Gene trapped
    68
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048247 VEGA Gene Model | MGI Sequence Detail 49237 C57BL/6J ±  kb
transcript OTTMUST00000123842 VEGA | MGI Sequence Detail 10654 Not Applicable  
polypeptide OTTMUSP00000067520 VEGA | MGI Sequence Detail 3271 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    121 from dbSNP Build 142
Protein
Information
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  • UniProt
    12 Sequences
  • InterPro Domains
    IPR017956 AT hook, DNA-binding motif
    IPR001650 Helicase, C-terminal
    IPR014012 Helicase/SANT-associated domain
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR000330 SNF2-related, N-terminal domain
Molecular
Reagents
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  • All nucleic 26
    cDNA 24
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
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MGI:2445189, MGI:3603830
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory