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Srcap
Gene Detail
Symbol

Name
ID
Srcap
Snf2-related CREBBP activator protein
MGI:2444036
Synonyms
B930091H02Rik, D030022P06Rik, F630004O05Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 7
69.56 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:127511983-127561219 bp, + strand
From VEGA annotation of GRCm38

  49237 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38213  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: SRCAP
Gene Tree: Srcap

Human
homologs
SRCAP, Snf2-related CREBBP activator protein
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 10847
neXtProt AC: NX_Q6ZRS2

Human Synonyms: DOMO1, EAF1, FLHS, SWR1

Human Chr (Location): 16p11.2; chr16:30699141-30740129 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SRCAP

Mutations,
alleles, and
phenotypes
All mutations/alleles(79) : Gene trapped(79)
Incidental mutations (data from APF )
Interactions
Srcap interacts with 344 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process biological_process
Component Golgi apparatus, nucleoplasm, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (16)    Tissues (8)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 16
cDNA source data(23)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase srcap ; ZFIN srcap    NEW 
Molecular
reagents
All nucleic(26) cDNA(24) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000048247 (Evidence)
Ensembl Gene Model ENSMUSG00000053877 (Evidence)
Entrez Gene 100043597 (Evidence)
Consensus CDS Project CCDS80806.1
International Mouse Phenotyping Consortium Status Srcap
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048247 VEGA Gene Model | MGI Sequence Detail 49237 C57BL/6J ±  kb
transcript OTTMUST00000123842 VEGA | MGI Sequence Detail 10654 Not Applicable 
polypeptide OTTMUSP00000067520 VEGA | MGI Sequence Detail 3271 Not Applicable 

For the selected sequences
All sequences(91) RefSeq(5) UniProt(14)
Polymorphisms
SNPs within 2kb(125 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017956 AT hook, DNA-binding motif
InterPro IPR020478 AT hook-like
InterPro IPR001650 Helicase, C-terminal
InterPro IPR014012 Helicase/SANT-associated domain
InterPro IPR014001 Helicase superfamily 1/2, ATP-binding domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR000330 SNF2-related, N-terminal domain
Protein Ontology PR:000015606 helicase SRCAP
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(27)
Other
accession IDs
MGI:2445189, MGI:3603830

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory