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Creb5 Gene Detail
Summary
  • Symbol
    Creb5
  • Name
    cAMP responsive element binding protein 5
  • Synonyms
    9430076C15Rik, Crebpa, D430026C09Rik
Location & Maps
more
  • Sequence Map
    Chr6:53287270-53700376 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      413107 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 25.90 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CREB5, cAMP responsive element binding protein 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CREB5, cAMP responsive element binding protein 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CREB-5, CRE-BPA
  • Links
    NCBI Gene ID: 9586
    neXtProt AC: NX_Q02930

  • Chr Location
    7p15.1; chr7:28299321-28825894 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 18215
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CREB5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotypes from multigenic genotypes
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display neonatal lethality.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000057134 VEGA Gene Model | MGI Sequence Detail 413107 C57BL/6J ±  kb
transcript OTTMUST00000140679 VEGA | MGI Sequence Detail 2648 Not Applicable  
polypeptide OTTMUSP00000073629 VEGA | MGI Sequence Detail 508 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    3397 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • InterPro Domains
    IPR004827 Basic-leucine zipper domain
    IPR016378 Transcription factor cyclic AMP-dependent, CRE-BP1-type
    IPR007087 Zinc finger, C2H2
    IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Molecular
Reagents
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  • All nucleic 31
    cDNA 31

    Microarray probesets 2
Other
Accession IDs
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MGI:2443551
References
more
  • Summaries
    All 25
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory