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Trem6l Gene Detail
Summary
  • Symbol
    Trem6l
  • Name
    triggering receptor expressed on myeloid cells-like 6
  • Synonyms
    B430306N03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443478
    NCBI Gene: 320148
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:48622310-48632580 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 23.99 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443478
 protein coding gene Chr17:48622310-48634052 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023868
 protein coding gene Chr17:49588525-49597094 (+)
A/J MGP_AJ_G0023828
 protein coding gene Chr17:48292616-48304489 (+)
AKR/J MGP_AKRJ_G0023796
 protein coding gene Chr17:48778593-48786430 (+)
BALB/cJ MGP_BALBcJ_G0023830
 protein coding gene Chr17:48218942-48226777 (+)
C3H/HeJ MGP_C3HHeJ_G0023593
 protein coding gene Chr17:49473276-49489104 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024273
 protein coding gene Chr17:51707893-51717992 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021722
 protein coding gene Chr17:45051273-45062453 (+)
CAST/EiJ MGP_CASTEiJ_G0023075
 protein coding gene Chr17:49658011-49674657 (+)
CBA/J MGP_CBAJ_G0023569
 protein coding gene Chr17:53550802-53566270 (+)
DBA/2J MGP_DBA2J_G0023698
 protein coding gene Chr17:47063015-47070846 (+)
FVB/NJ MGP_FVBNJ_G0023664
 protein coding gene Chr17:46724559-46736243 (+)
LP/J MGP_LPJ_G0023778
 protein coding gene Chr17:50297513-50308561 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023692
 protein coding gene Chr17:53038175-53049001 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024319
 protein coding gene Chr17:49104361-49115202 (+)
PWK/PhJ MGP_PWKPhJ_G0022820
 protein coding gene Chr17:46497896-46509052 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022634
 protein coding gene Chr17:46006493-46017094 (+)
WSB/EiJ MGP_WSBEiJ_G0023139
 protein coding gene Chr17:49704563-49712533 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 320148 NCBI Gene Model | MGI Sequence Detail 10271 C57BL/6J ±  kb
transcript NM_177083 RefSeq | MGI Sequence Detail 2441 C57BL/6  
polypeptide NP_796057 RefSeq | MGI Sequence Detail 289 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:345072 Kasamatsu J, et al., Double-stranded RNA analog and type I interferon regulate expression of Trem paired receptors in murine myeloid cells. BMC Immunol. 2016 May 3;17(1):9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory