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Gimap5
Gene Detail
Symbol

Name
ID
Gimap5
GTPase, IMAP family member 5
MGI:2442232
Synonyms
E230026N22Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 6
23.71 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:48746197-48754210 bp, + strand
From VEGA annotation of GRCm38

  8014 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41257  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle; 1 dog; 2 chicken

HCOP human homology predictions: GIMAP1-GIMAP5
Gene Tree: Gimap5

Human
homologs
GIMAP1-GIMAP5, GIMAP1-GIMAP5 readthrough
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 100527949

Human Chr (Location): 7q; chr7:150716557-150743649 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Chemically induced (ENU)(1) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygouse for a knock-out allele display defects in lymphocyte development with hematopoietic defects and reduced life span. Mice homozygous for an ENU-induced allele exhibit premature death associated with extramedullary hematopoiesis in the liver, anemia, cachexia, and colitis.
 
Interactions
Gimap5 interacts with 128 markers (Mir7-1, Mir10a, Mir10b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Component integral component of membrane, lysosome, ...
Function GTP binding, nucleotide binding
External Resources: FuncBase
Expression
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000026930 (Evidence)
Ensembl Gene Model ENSMUSG00000043505 (Evidence)
Entrez Gene 317757 (Evidence)
UniGene 455917
DFCI TC1584584, TC1628452, TC1599160
DoTS DT.40180190, DT.87025704, DT.94354785
Consensus CDS Project CCDS20114.1
International Mouse Phenotyping Consortium Status Gimap5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026930 VEGA Gene Model | MGI Sequence Detail 8014 C57BL/6J ±  kb
transcript OTTMUST00000066585 VEGA | MGI Sequence Detail 1953 Not Applicable 
polypeptide OTTMUSP00000033393 VEGA | MGI Sequence Detail 308 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(11) UniProt(1)
Polymorphisms
SNPs within 2kb(58 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006703 AIG1
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000007979 GTPase IMAP family member 5
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:209926 Yano K, et al., Gimap3 and Gimap5 cooperate to maintain T-cell numbers in the mouse. Eur J Immunol. 2014 Feb;44(2):561-72
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory