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Azin2 Gene Detail
Summary
  • Symbol
    Azin2
  • Name
    antizyme inhibitor 2
  • Synonyms
    4933429I20Rik, Adc, AZIN2, Odcp
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442093
    NCBI Gene: 242669
  • Gene Overview
    MyGene.info: AZIN2
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr4:128930233-128962442 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      32210 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 62.48 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    AZIN2, antizyme inhibitor 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AZIN2, antizyme inhibitor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ADC, AZI2, AZIB1, ODC1L, ODCp, ODC-p
  • Links
    NCBI Gene ID: 113451
    neXtProt AC: NX_Q96A70
    UniProt: Q96A70

  • Chr Location
    1p35.1; chr1:33081110-33162288 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit decreased circulating insulin levels.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000009540 VEGA Gene Model | MGI Sequence Detail 32210 C57BL/6J ±  kb
    transcript OTTMUST00000022112 VEGA | MGI Sequence Detail 2049 Not Applicable  
    polypeptide OTTMUSP00000010078 VEGA | MGI Sequence Detail 459 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      497 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 17
      Primer pair 2

      Microarray probesets 4
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 3
      Gene Ontology 10
      Phenotypes 13
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:238263 Acosta-Andrade C, et al., A novel role for antizyme inhibitor 2 as a regulator of serotonin and histamine biosynthesis and content in mouse mast cells. Amino Acids. 2016 Oct;48(10):2411-21

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    06/12/2018
    MGI 6.12
    The Jackson Laboratory