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G3bp2
Gene Detail
Symbol

Name
ID
G3bp2
GTPase activating protein (SH3 domain) binding protein 2
MGI:2442040
Synonyms
E430034L04Rik, G3BP, G3BP2
Feature Type
protein coding gene
Genetic Map
Chromosome 5
45.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr5:92052146-92083735 bp, - strand
From Ensembl annotation of GRCm38

  31590 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:137244  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: G3bp2

Human
homologs
Human Homolog G3BP2, GTPase activating protein (SH3 domain) binding protein 2
NCBI Gene ID 9908
neXtProt AC  NX_Q9UN86
Human Chr (Location)  4q21.1; chr4:75642769-75724525 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(234) : Gene trapped(232) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
G3bp2 interacts with 438 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process mRNA transport, small GTPase mediated signal transduction, ...
Component cytoplasm, intracellular
Function nucleic acid binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (23)    Tissues (23)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 21
RT-PCR 2
cDNA source data(23)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(25) cDNA(24) Primer pair(1)
Microarray probesets(6)
Other database
links
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029405 Ensembl Gene Model | MGI Sequence Detail 31590 C57BL/6J ±  kb
transcript ENSMUST00000169094 Ensembl | MGI Sequence Detail 4331 Not Applicable 
polypeptide ENSMUSP00000128244 Ensembl | MGI Sequence Detail 482 Not Applicable 

For the selected sequences
All sequences(97) RefSeq(14) UniProt(13)
Polymorphisms
SNPs within 2kb(124 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002075 Nuclear transport factor 2
InterPro IPR018222 Nuclear transport factor 2, Eukaryote
InterPro IPR012677 Nucleotide-binding, alpha-beta plait
InterPro IPR000504 RNA recognition motif domain
Protein Ontology PR:000007744 ras GTPase-activating protein-binding protein 2
References
(Earliest) J:57569 Kennedy D, et al., Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif. Biomed Pept Proteins Nucleic Acids. 1996-97;2(3):93-9
(Latest) J:201630 Ryder E, et al., Molecular characterization of mutant mouse strains generated from the EUCOMM/KOMP-CSD ES cell resource. Mamm Genome. 2013 Aug;24(7-8):286-94
All references(41)
Other
accession IDs
MGI:1346339, MGI:2146760

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory