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Daglb
Gene Detail
Symbol

Name
ID
Daglb
diacylglycerol lipase, beta
MGI:2442032
Synonyms
E330036I19Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 5
82.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:143472947-143504442 bp, + strand
From VEGA annotation of GRCm38

  31496 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:34715  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DAGLB
Gene Tree: Daglb

Human
homologs
DAGLB, diacylglycerol lipase, beta
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 221955
neXtProt AC: NX_Q8NCG7

Human Synonyms: DAGLBETA, KCCR13L

Human Chr (Location): 7p22.1; chr7:6409116-6448012 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for null mutations have a reduction in endocannabinoids in the brain and a decrease in adult neuronal proliferation in the hippocampus.
 
Interactions
Daglb interacts with 174 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (61)    Tissues (8)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 51
RT-PCR 10
cDNA source data(9)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase daglb    NEW 
Molecular
reagents
All nucleic(11) cDNA(10) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000021320 (Evidence)
Ensembl Gene Model ENSMUSG00000039206 (Evidence)
Entrez Gene 231871 (Evidence)
EC 3.1.1.-
Consensus CDS Project CCDS39370.1
International Mouse Phenotyping Consortium Status Daglb
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021320 VEGA Gene Model | MGI Sequence Detail 31496 C57BL/6J ±  kb
transcript OTTMUST00000050543 VEGA | MGI Sequence Detail 2806 Not Applicable 
polypeptide OTTMUSP00000023608 VEGA | MGI Sequence Detail 587 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(315 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002921 Lipase, class 3
Protein Ontology PR:000006269 sn1-specific diacylglycerol lipase beta
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:189393 Yoshino H, et al., Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex. J Physiol. 2011 Oct 15;589(Pt 20):4857-84
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory