Hydin
Gene Detail

Symbol Name ID

Hydin HYDIN, axonemal central pair apparatus protein MGI:2389007

Synonyms

1700034M11Rik, 4930545D19Rik, hy3, hy-3, hyrh

Feature Type

protein coding gene

Genetic Map

Chromosome 8

57.50 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr8:110266977-110610253 bp, + strand From NCBI annotation of GRCm38   343277 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:52118  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Hydin

Alleles and phenotypes

All alleles(7) : Targeted(1) Gene trapped(3) Transgenic(1) Spontaneous(2)
 

Mice homozygous for a mutation in this gene develop hydrocephaly after birth. Symptoms develop after 3-5 days. Affected animals usually die before 2 months of age.

 
Human Diseases Modeled Using Mouse Hydin (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(7)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	brain development, cilium assembly, ...
Component	cellular_component
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (36)    Tissues (4)    Images (13)
Theiler Stages: 23

Assay Type	Results
RNA in situ	36

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(7) Genomic(2) cDNA(5)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000059854 (Evidence)
Entrez Gene	244653 (Evidence)
DFCI	TC1588015, TC1592965, TC1600621
DoTS	DT.55248506, DT.91284276, DT.94155718, DT.94164236
NIA Mouse Gene Index	U009821, U030244
Consensus CDS Project	CCDS40476.1
International Mouse Knockout Project Status	Hydin

Sequences

Length	Strain/Species
genomic	244653	NCBI Gene Model | MGI Sequence Detail	343277	C57BL/6J
transcript	NM_172916	RefSeq | MGI Sequence Detail	15783	Not Specified
polypeptide	Q80W93	UniProt | EBI | MGI Sequence Detail	5154	Not Applicable

All sequences(24) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(1102 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR008962	PapD-like
Protein Ontology	PR:000008872	hydrocephalus-inducing protein

Graphical View of Protein Domain Structure

References

(Earliest) J:13035 Gruneberg H, Two new mutant genes in the house mouse. J Genet. 1943;45:22-28
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(37)

Other accession IDs

MGD-MRK-11026, MGD-MRK-11029, MGI:1922491, MGI:1923961, MGI:2157966, MGI:3801607, MGI:96295