About   Help   FAQ
Hydin
Gene Detail
Symbol

Name
ID
Hydin
HYDIN, axonemal central pair apparatus protein
MGI:2389007
Synonyms
1700034M11Rik, 4930545D19Rik, hy3, hy-3, hyrh
Feature Type
protein coding gene
Genetic Map
Chromosome 8
57.50 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr8:110266977-110610253 bp, + strand
From NCBI annotation of GRCm38

  343277 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:52118  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: HYDIN
Gene Tree: Hydin

Human
homologs
HYDIN, HYDIN, axonemal central pair apparatus protein
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 54768
neXtProt AC: NX_Q4G0P3

Human Synonyms: CILD5, HYDIN1, HYDIN2, PPP1R31

Human Chr (Location): 16q22.2; chr16:70802084-71230722 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human HYDIN

Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(3) Spontaneous(2) Targeted(3) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a mutation in this gene develop hydrocephaly after birth. Symptoms develop after 3-5 days. Affected animals usually die before 2 months of age.
 
Phenotype Images(7)
Interactions
Hydin interacts with 207 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process axoneme assembly, brain development, ...
Component axonemal central pair projection, cell projection
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (36)    Tissues (4)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 36
cDNA source data(4)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase hydin    NEW 
Molecular
reagents
All nucleic(7) Genomic(2) cDNA(5)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000059854 (Evidence)
Entrez Gene 244653 (Evidence)
DFCI TC1600621, TC1592965, TC1588015
DoTS DT.94155718, DT.91284276, DT.55248506, DT.94164236
NIA Mouse Gene Index U009821, U030244
Consensus CDS Project CCDS40476.1
International Mouse Phenotyping Consortium Status Hydin
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 244653 NCBI Gene Model | MGI Sequence Detail 343277 C57BL/6J ±  kb
transcript NM_172916 RefSeq | MGI Sequence Detail 15783 Not Specified 
polypeptide Q80W93 UniProt | EBI | MGI Sequence Detail 5154 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(1192 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000535 Major sperm protein
InterPro IPR008962 PapD-like
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000008872 hydrocephalus-inducing protein
Graphical View of Protein Domain Structure
References
(Earliest) J:13035 Gruneberg H, Two new mutant genes in the house mouse. J Genet. 1943;45:22-28
(Latest) J:215970 Recla JM, et al., Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene. Mamm Genome. 2014 Jun;25(5-6):211-22
All references(37)
Other
accession IDs
MGD-MRK-11026, MGD-MRK-11029, MGI:1922491, MGI:1923961, MGI:2157966, MGI:3801607, MGI:96295

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/30/2015
MGI 5.22
The Jackson Laboratory