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Wac
Gene Detail
 Symbol
Name
ID
Wac
WW domain containing adaptor with coiled-coil
MGI:2387357
Synonyms 1110067P07Rik, A230035H12Rik, Wwp4
Feature Type protein coding gene
Genetic Map
Chromosome 18
4.62 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr18:7868832-7973547 bp, + strand
From VEGA annotation of GRCm38

  104716 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41148  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Wac

Human
homologs
Human Homolog WAC, WW domain containing adaptor with coiled-coil
NCBI Gene ID 51322
neXtProt AC  NX_Q9BTA9
Human Synonyms  BM-016, PRO1741, Wwp4
Human Chr (Location)  10p12.1-p11.2; chr10:28532426-28623112 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(54) : Gene trapped(51) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Wac interacts with 399 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cellular response to DNA damage stimulus, chromatin modification, ...
Component nucleus, spliceosomal complex
Function chromatin binding, RNA polymerase II core binding
External Resources: FuncBase
Expression
cDNA source data(21)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) cDNA(21)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000036803 (Evidence)
Ensembl Gene ModelENSMUSG00000024283 (Evidence)
Entrez Gene225131 (Evidence)
DFCITC1574738, TC1600993, TC1611328, TC1629496, TC1666677, TC1727274
Consensus CDS ProjectCCDS29046.1, CCDS50218.1, CCDS70869.1
International Mouse Knockout Project StatusWac
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036803 VEGA Gene Model | MGI Sequence Detail 104716 C57BL/6J ±  kb
transcript OTTMUST00000094454 VEGA | MGI Sequence Detail 5208 Not Applicable 
polypeptide OTTMUSP00000052531 VEGA | MGI Sequence Detail 646 Not Applicable 

For the selected sequences
All sequences(135) RefSeq(16) UniProt(12)
Polymorphisms SNPs within 2kb(550 from dbSNP Build 137)    SNPs within 2kb including multiple locations(554)
Protein-related
information
ResourceIDDescription
InterPro IPR001202 WW domain
Protein Ontology PR:000031681 WW domain-containing adapter protein with coiled-coil
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:175602 Totsukawa G, et al., VCIP135 deubiquitinase and its binding protein, WAC, in p97ATPase-mediated membrane fusion. EMBO J. 2011;30(17):3581-93
All references(39)
Other
accession IDs
MGI:1923581, MGI:2147203, MGI:2147204

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory