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Ndufs2
Gene Detail
 Symbol
Name
ID
Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
MGI:2385112
Synonyms MGC:27667
Feature Type protein coding gene
Genetic Map
Chromosome 1
79.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:171234853-171247122 bp, - strand
From VEGA annotation of GRCm38

  12270 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56659  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: [NiFe]-hydrogenase-3-type complex, large subunit/NADH:quinone oxidoreductase (complex I), 49K/NdhH/NuoD subunit
Gene Tree: Ndufs2

Human
homologs
Human Homolog NDUFS2, NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NCBI Gene ID 4720
neXtProt AC  NX_O75306
Human Synonyms  CI-49
Human Chr (Location)  1q23; chr1:161197419-161214395 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human NDUFS2
Alleles
and
phenotypes
All alleles(17) : Gene trapped(17)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process oxidation-reduction process, response to oxidative stress, ...
Component membrane, mitochondrial inner membrane, ...
Function 4 iron, 4 sulfur cluster binding, iron-sulfur cluster binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (102)    Tissues (102)    Images (16)
Theiler Stages: 3, 4, 5, 22, 23
Assay TypeResults
RNA in situ 95
RT-PCR 7
cDNA source data(314)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(317) cDNA(314) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000021571 (Evidence)
Ensembl Gene ModelENSMUSG00000013593 (Evidence)
Entrez Gene226646 (Evidence)
UniGene21669
DFCITC1573275
DoTSDT.110838375, DT.536843, DT.94378964, DT.97402292, DT.99864856
NIA Mouse Gene IndexU022047
EC1.6.5.3, 1.6.99.3
Consensus CDS ProjectCCDS15484.1
International Mouse Knockout Project StatusNdufs2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021571 VEGA Gene Model | MGI Sequence Detail 12270 C57BL/6J ±  kb
transcript OTTMUST00000051199 VEGA | MGI Sequence Detail 1623 Not Applicable 
polypeptide OTTMUSP00000024040 VEGA | MGI Sequence Detail 463 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(4) UniProt(3)
Polymorphisms SNPs within 2kb(322 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001135 NADH-quinone oxidoreductase, subunit D
InterPro IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site
InterPro IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H
Protein Ontology PR:000011097 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:172354 Wirtz S, et al., Region-Specific Expression of Mitochondrial Complex I Genes during Murine Brain Development. PLoS One. 2011;6(4):e18897
All references(38)
Other
accession IDs
MGI:2138402

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory