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Ndufs2
Gene Detail
Symbol

Name
ID
Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
MGI:2385112
Synonyms
MGC:27667
Feature Type
protein coding gene
Genetic Map
Chromosome 1
79.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:171234853-171251388 bp, - strand
From VEGA annotation of GRCm38

  16536 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:56659  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NDUFS2
Protein SuperFamily: [NiFe]-hydrogenase-3-type complex, large subunit/NADH:quinone oxidoreductase (complex I), 49K/NdhH/NuoD subunit
Gene Tree: Ndufs2

Human
homologs
NDUFS2, NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 4720
neXtProt AC: NX_O75306

Human Synonyms: CI-49

Human Chr (Location): 1q23; chr1:161197419-161214395 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NDUFS2

Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(21)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ndufs2 interacts with 40 markers (Mir1b, Mir32, Mir92-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (98)    Tissues (98)    Images (16)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 95
RT-PCR 3
cDNA source data(314)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ndufs2    NEW 
Molecular
reagents
All nucleic(317) cDNA(314) Primer pair(3)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000021571 (Evidence)
Ensembl Gene Model ENSMUSG00000013593 (Evidence)
Entrez Gene 226646 (Evidence)
UniGene 21669
DFCI TC1573275
DoTS DT.110838375, DT.536843, DT.94378964, DT.97402292, DT.99864856
NIA Mouse Gene Index U022047
EC 1.6.5.3, 1.6.99.3
Consensus CDS Project CCDS15484.1
International Mouse Phenotyping Consortium Status Ndufs2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021571 VEGA Gene Model | MGI Sequence Detail 16536 C57BL/6J ±  kb
transcript OTTMUST00000051199 VEGA | MGI Sequence Detail 1623 Not Applicable 
polypeptide OTTMUSP00000024040 VEGA | MGI Sequence Detail 463 Not Applicable 

For the selected sequences
All sequences(75) RefSeq(2) UniProt(4)
Polymorphisms
SNPs within 2kb(356 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001135 NADH-quinone oxidoreductase, subunit D
InterPro IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site
InterPro IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H
InterPro IPR029014 NiFe hydrogenase-like
Protein Ontology PR:000011097 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:172354 Wirtz S, et al., Region-Specific Expression of Mitochondrial Complex I Genes during Murine Brain Development. PLoS One. 2011;6(4):e18897
All references(36)
Other
accession IDs
MGI:2138402

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory