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Prpsap2
Gene Detail
 Symbol
Name
ID
Prpsap2
phosphoribosyl pyrophosphate synthetase-associated protein 2
MGI:2384838
Synonyms A230054F23Rik, MGC:36957
Feature Type protein coding gene
Genetic Map
Chromosome 11
37.96 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:61729654-61762062 bp, - strand
From VEGA annotation of GRCm38

  32409 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2073  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: ribose-phosphate pyrophosphokinase catalytic chain
Gene Tree: Prpsap2

Human
homologs
Human Homolog PRPSAP2, phosphoribosyl pyrophosphate synthetase-associated protein 2
NCBI Gene ID 5636
neXtProt AC  NX_O60256
Human Synonyms  PAP41
Human Chr (Location)  17p11.2-p12; chr17:18856299-18931287 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(4) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prpsap2 interacts with 94 markers (Mir27a, Mir27b, Mir34a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process bone development, nucleotide biosynthetic process
Component protein complex, ribose phosphate diphosphokinase complex
Function magnesium ion binding, ribose phosphate diphosphokinase activity
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (93)    Tissues (39)    Images (21)
Theiler Stages: 23, 26, 28
Assay TypeResults
RNA in situ 93
cDNA source data(64)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(65) cDNA(65)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000005840 (Evidence)
Ensembl Gene ModelENSMUSG00000020528 (Evidence)
Entrez Gene212627 (Evidence)
UniGene27703
DFCITC1576992, TC1615927
DoTSDT.101286684, DT.101311400, DT.110725328, DT.531900, DT.87031972
NIA Mouse Gene IndexU032894, U079429
Consensus CDS ProjectCCDS24819.1
International Mouse Knockout Project StatusPrpsap2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005840 VEGA Gene Model | MGI Sequence Detail 32409 C57BL/6J ±  kb
transcript OTTMUST00000012991 VEGA | MGI Sequence Detail 1837 Not Applicable 
polypeptide OTTMUSP00000006040 VEGA | MGI Sequence Detail 369 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(14) UniProt(4)
Polymorphisms SNPs within 2kb(82 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005946 Ribose-phosphate diphosphokinase
Protein Ontology PR:000013295 phosphoribosyl pyrophosphate synthase-associated protein 2
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:188142 Bassett JH, et al., Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength. PLoS Genet. 2012 Aug;8(8):e1002858
All references(37)
Other
accession IDs
MGI:2443765

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory