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Eif4g1
Gene Detail
Symbol

Name
ID
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
MGI:2384784
Synonyms
E030015G23Rik, MGC:37551
Feature Type
protein coding gene
Genetic Map
Chromosome 16
12.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:20668313-20692884 bp, + strand
From VEGA annotation of GRCm38

  24572 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:110725  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: EIF4G1
Gene Tree: Eif4g1

Human
homologs
EIF4G1, eukaryotic translation initiation factor 4 gamma, 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 1981
neXtProt AC: NX_Q04637

Human Synonyms: EIF4F, EIF4G, EIF-4G1, EIF4GI, P220, PARK18

Human Chr (Location): 3q27.1; chr3:184314495-184335358 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human EIF4G1

Mutations,
alleles, and
phenotypes
All mutations/alleles(49) : Gene trapped(47) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Eif4g1 interacts with 251 markers (Mir10b, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(476)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase eif4g3    NEW 
Molecular
reagents
All nucleic(476) cDNA(476)
Microarray probesets(7)
Other database
links
VEGA Gene Model OTTMUSG00000024386 (Evidence)
Ensembl Gene Model ENSMUSG00000045983 (Evidence)
Entrez Gene 208643 (Evidence)
UniGene 260256
DFCI TC1608401, TC1573322, TC1587521
DoTS DT.101255368, DT.101175376, DT.102535766, DT.94369854, DT.94240024, DT.487187, DT.102542692
NIA Mouse Gene Index U016930
Consensus CDS Project CCDS28054.1, CCDS28055.1
International Mouse Phenotyping Consortium Status Eif4g1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024386 VEGA Gene Model | MGI Sequence Detail 24572 C57BL/6J ±  kb
transcript OTTMUST00000060049 VEGA | MGI Sequence Detail 5638 Not Applicable 
polypeptide OTTMUSP00000029549 VEGA | MGI Sequence Detail 1600 Not Applicable 

For the selected sequences
All sequences(155) RefSeq(30) UniProt(20)
Polymorphisms
SNPs within 2kb(68 from dbSNP Build 137)    SNPs within 2kb including multiple locations(70)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR003891 Initiation factor eIF-4 gamma, MA3
InterPro IPR003890 MIF4G-like, type 3
InterPro IPR016021 MIF4-like, type 1/2/3
InterPro IPR003307 W2 domain
Protein Ontology PR:000006998 eukaryotic translation initiation factor 4 gamma 1
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:217461 Yang G, et al., An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program. Neuron. 2014 Nov 19;84(4):723-39
All references(40)
Other
accession IDs
MGI:2443563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory