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Kank2
Gene Detail
Symbol

Name
ID
Kank2
KN motif and ankyrin repeat domains 2
MGI:2384568
Synonyms
Ankrd25, MGC:12143, MGC:7734
Feature Type
protein coding gene
Genetic Map
Chromosome 9
7.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:21766773-21798546 bp, - strand
From NCBI annotation of GRCm38

  31774 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9163  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Kank2

Human
homologs
Human Homolog KANK2, KN motif and ankyrin repeat domains 2
NCBI Gene ID 25959
neXtProt AC  NX_Q63ZY3
Human Synonyms  ANKRD25, MXRA3, PPKWH, SIP
Human Chr (Location)  19p13.2; chr19:11164267-11197567 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(67) : Gene trapped(65) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Kank2 interacts with 240 markers (Mir7-1, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process apoptotic process, negative regulation of cell proliferation, ...
Component cytoplasm, mitochondrion
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (5)    Tissues (5)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 5
cDNA source data(28)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(28) cDNA(28)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000032194 (Evidence)
Entrez Gene235041 (Evidence)
UniGene257371
DFCITC1688392, TC1582251, TC1714779
DoTSDT.94167132, DT.488593, DT.101364200
NIA Mouse Gene IndexU030590
Consensus CDS ProjectCCDS22911.1
International Mouse Knockout Project StatusKank2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 235041 NCBI Gene Model | MGI Sequence Detail 31774 C57BL/6J ±  kb
transcript NM_145611 RefSeq | MGI Sequence Detail 4853 C57BL/6 
polypeptide Q8BX02 UniProt | EBI | MGI Sequence Detail 843 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(82 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002110 Ankyrin repeat
InterPro IPR020683 Ankyrin repeat-containing domain
InterPro IPR021939 Kank N-terminal motif
Protein Ontology PR:000032283 KN motif and ankyrin repeat domain-containing protein 2
Graphical View of Protein Domain Structure
References
(Earliest) J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(40)
Other
accession IDs
MGI:2143085

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory