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Spsb4 Gene Detail
Summary
  • Symbol
    Spsb4
  • Name
    splA/ryanodine receptor domain and SOCS box containing 4
  • Synonyms
    D030068E18Rik, Ssb4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2183445
    NCBI Gene: 211949
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:96825535-96900408 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 50.74 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    950 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2183445
 protein coding gene Chr9:96825535-96900896 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035148
 protein coding gene Chr9:98185582-98262253 (-)
A/J MGP_AJ_G0035130
 protein coding gene Chr9:94736237-94812256 (-)
AKR/J MGP_AKRJ_G0035061
 protein coding gene Chr9:97042856-97118673 (-)
BALB/cJ MGP_BALBcJ_G0035122
 protein coding gene Chr9:94414622-94489983 (-)
C3H/HeJ MGP_C3HHeJ_G0034832
 protein coding gene Chr9:97449917-97525956 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035642
 protein coding gene Chr9:100990994-101069333 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032542
 protein coding gene Chr9:92562621-92638588 (-)
CAST/EiJ MGP_CASTEiJ_G0034144
 protein coding gene Chr9:97246219-97324112 (-)
CBA/J MGP_CBAJ_G0034800
 protein coding gene Chr9:104489659-104569837 (-)
DBA/2J MGP_DBA2J_G0034962
 protein coding gene Chr9:94255584-94330769 (-)
FVB/NJ MGP_FVBNJ_G0034910
 protein coding gene Chr9:93103345-93179319 (-)
LP/J MGP_LPJ_G0035041
 protein coding gene Chr9:98429024-98508009 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034949
 protein coding gene Chr9:106470520-106548191 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035664
 protein coding gene Chr9:97284841-97362425 (-)
PWK/PhJ MGP_PWKPhJ_G0033851
 protein coding gene Chr9:94451178-94526375 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033686
 protein coding gene Chr9:97341584-97420491 (-)
WSB/EiJ MGP_WSBEiJ_G0034264
 protein coding gene Chr9:97151103-97227873 (-)



Homology
more
  • Human Ortholog
    SPSB4, splA/ryanodine receptor domain and SOCS box containing 4
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPSB4, splA/ryanodine receptor domain and SOCS box containing 4
  • Synonyms
    SSB4, SSB-4
  • Links
    NCBI Gene ID: 92369
    neXtProt AC: NX_Q96A44
    UniProt: Q96A44

  • Chr Location
    3q23; chr3:141051347-141148611 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    17
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 211949 NCBI Gene Model | MGI Sequence Detail 74874 C57BL/6J ±  kb
transcript NM_145134 RefSeq | MGI Sequence Detail 2232 C57BL/6  
polypeptide Q8R5B6 UniProt | EBI | MGI Sequence Detail 273 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 3
Other
Accession IDs
less
MGI:2443137
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory