Ash1l
Gene Detail

Symbol Name ID

Ash1l ash1 (absent, small, or homeotic)-like (Drosophila) MGI:2183158

Synonyms

8030453L17Rik, chromatin remodeling factor, E430018P19Rik, KMT2H

Feature Type

protein coding gene

Genetic Map

Chromosome 3

39.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr3:88965812-89079373 bp, + strand From Ensembl annotation of GRCm38   113562 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:10225  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ash1l

Human homologs

Human Homolog		ASH1L, ash1 (absent, small, or homeotic)-like (Drosophila)
NCBI Gene ID		55870
neXtProt AC		NX_Q9NR48
Human Synonyms		ASH1, ASH1L1, KMT2H
Human Chr (Location)		1q22; chr1:155305052-155532324 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(6) : Targeted(1) Gene trapped(5)

Gene Ontology (GO) classifications

All GO classifications: (17 annotations)

Process	chromatin modification, methylation, ...
Component	cell junction, chromosome, ...
Function	DNA binding, histone-lysine N-methyltransferase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (133)    Tissues (122)    Images (2)
Theiler Stages: 2, 3, 4, 5, 22, 23, 28

Assay Type	Results
RNA in situ	118
RT-PCR	15

cDNA source data(122)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(123) cDNA(122) Primer pair(1)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000028053 (Evidence)
Entrez Gene	192195 (Evidence)
UniGene	130752
DFCI	TC1577773, TC1598084, TC1598302, TC1654948, TC1729883
DoTS	DT.101378611, DT.101707537, DT.101716224, DT.40151644, DT.94231836
NIA Mouse Gene Index	U220219
EC	2.1.1.43
Consensus CDS Project	CCDS17487.1
International Mouse Knockout Project Status	Ash1l

Sequences

Length	Strain/Species
genomic	ENSMUSG00000028053	Ensembl Gene Model | MGI Sequence Detail	113562	C57BL/6J
transcript	ENSMUST00000090933	Ensembl | MGI Sequence Detail	11268	Not Applicable
polypeptide	ENSMUSP00000088451	Ensembl | MGI Sequence Detail	2958	Not Applicable

All sequences(40) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(385 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR017956	AT hook, DNA-binding motif
InterPro	IPR006560	AWS
InterPro	IPR001025	Bromo adjacent homology (BAH) domain
InterPro	IPR001487	Bromodomain
InterPro	IPR003616	Post-SET domain
InterPro	IPR001214	SET domain
InterPro	IPR011011	Zinc finger, FYVE/PHD-type
InterPro	IPR019787	Zinc finger, PHD-finger
InterPro	IPR001965	Zinc finger, PHD-type
InterPro	IPR019786	Zinc finger, PHD-type, conserved site
InterPro	IPR013083	Zinc finger, RING/FYVE/PHD-type
Protein Ontology	PR:000030913	histone-lysine N-methyltransferase ASH1L

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(37)

Other accession IDs

MGI:2442216, MGI:2444414