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Xpnpep2
Gene Detail
 Symbol
Name
ID
Xpnpep2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
MGI:2180001
Synonyms 9030008G12Rik, mAPP
Feature Type protein coding gene
Genetic Map
Chromosome X
25.52 cM, cytoband A3.2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
ChrX:48108725-48136981 bp, + strand
From VEGA annotation of GRCm38

  28257 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37766  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: pig X-Pro aminopeptidase
Gene Tree: Xpnpep2

Human
homologs
Human Homolog XPNPEP2, X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
NCBI Gene ID 7512
neXtProt AC  NX_O43895
Human Synonyms  AEACEI, APP2
Human Chr (Location)  Xq25; chrX:129738970-129769549 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human XPNPEP2
Alleles
and
phenotypes
All alleles(3) : Targeted(2) Gene trapped(1)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process proteolysis
Component extracellular vesicular exosome
Function aminopeptidase activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (28)    Tissues (7)    Images (18)
Theiler Stages: 23
Assay TypeResults
RNA in situ 28
cDNA source data(11)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000017507 (Evidence)
Ensembl Gene ModelENSMUSG00000037005 (Evidence)
Entrez Gene170745 (Evidence)
UniGene129279
DFCITC1583628, TC1739667
DoTSDT.101237170, DT.101721278, DT.91339563
NIA Mouse Gene IndexU019834
EC3.4.11.9
Consensus CDS ProjectCCDS30106.1
International Mouse Knockout Project StatusXpnpep2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017507 VEGA Gene Model | MGI Sequence Detail 28257 C57BL/6J ±  kb
transcript OTTMUST00000042503 VEGA | MGI Sequence Detail 3184 Not Applicable 
polypeptide OTTMUSP00000019100 VEGA | MGI Sequence Detail 741 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(8) UniProt(8)
Polymorphisms SNPs within 2kb(409 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000587 Creatinase
InterPro IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site
InterPro IPR000994 Peptidase M24, structural domain
Protein Ontology PR:000017496 Xaa-Pro aminopeptidase 2
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:178354 Sherwood RI, et al., Wnt signaling specifies and patterns intestinal endoderm. Mech Dev. 2011 Sep;128(7-10):387-400
All references(31)
Other
accession IDs
MGI:2442316

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory