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Mill2 Gene Detail
Summary
  • Symbol
    Mill2
  • Name
    MHC I like leukocyte 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2179989
    NCBI Gene: 243864
  • Gene Overview
    MyGene.info: MICB
Location & Maps
more
  • Sequence Map
    Chr7:18839966-18863113 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      23148 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 9.35 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    MICB, MHC class I polypeptide-related sequence B
  • Vertebrate Orthologs
    7
  • Human Ortholog
    MICB, MHC class I polypeptide-related sequence B
    Orthology source: HomoloGene
  • Synonyms
    PERB11.2
  • Links
    NCBI Gene ID: 4277
    neXtProt AC: NX_Q29980

  • Chr Location
    6p21.3; chr6:31494277-31511124 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
  • All Mutations and Alleles
    1
  • Gene trapped
    1
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000058434 VEGA Gene Model | MGI Sequence Detail 23148 C57BL/6J ±  kb
transcript OTTMUST00000143503 VEGA | MGI Sequence Detail 1121 Not Applicable  
polypeptide OTTMUSP00000074801 VEGA | MGI Sequence Detail 355 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    204 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR013783 Immunoglobulin-like fold
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR027648 MHC class I alpha chain
    IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
    IPR011161 MHC class I-like antigen recognition-like
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 17
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:79325 Kasahara M, et al., A family of MHC class I-like genes located in the vicinity of the mouse leukocyte receptor complex. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13687-92
  • Latest
    J:177498 Martinez-Naves E, et al., Recognition of the ligand-type specificity of classical and non-classical MHC I proteins. FEBS Lett. 2011 Nov 4;585(21):3478-84

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory