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Mill2 Gene Detail
Summary
  • Symbol
    Mill2
  • Name
    MHC I like leukocyte 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2179989
    NCBI Gene: 243864
  • Gene Overview
    MyGene.info: MICB
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:18839966-18865402 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 9.35 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    241 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2179989
protein coding gene Chr7:18839956-18869696 (.)
129S1/SvImJ MGP_129S1SvImJ_G0031745
protein coding gene Chr7:16759423-16789070 (+)
A/J MGP_AJ_G0031721
protein coding gene Chr7:16478700-16501563 (+)
AKR/J MGP_AKRJ_G0031647
protein coding gene Chr7:16925416-16948965 (+)
BALB/cJ MGP_BALBcJ_G0031726
protein coding gene Chr7:16660950-16683904 (+)
C3H/HeJ MGP_C3HHeJ_G0031448
protein coding gene Chr7:17167006-17192109 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032192
protein coding gene Chr7:17647366-17678486 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0030791
protein coding gene Chr7:13577514-13605093 (+)
CBA/J MGP_CBAJ_G0031410
protein coding gene Chr7:18269033-18294094 (+)
DBA/2J MGP_DBA2J_G0031565
protein coding gene Chr7:16413464-16438825 (+)
FVB/NJ MGP_FVBNJ_G0031517
protein coding gene Chr7:16261923-16291891 (+)
LP/J MGP_LPJ_G0031648
protein coding gene Chr7:17122799-17145317 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031553
protein coding gene Chr7:18155742-18181277 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032220
protein coding gene Chr7:16522392-16552991 (+)
PWK/PhJ MGP_PWKPhJ_G0030515
protein coding gene Chr7:13491017-13516803 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030342
protein coding gene Chr7:11202627-11227233 (+)
WSB/EiJ MGP_WSBEiJ_G0030891
protein coding gene Chr7:16717120-16745168 (+)



Homology
more
  • Human Ortholog
    MICB, MHC class I polypeptide-related sequence B
  • Vertebrate Orthologs
    7
  • Human Ortholog
    MICB, MHC class I polypeptide-related sequence B
    Orthology source: HomoloGene
  • Synonyms
    PERB11.2
  • Links
    NCBI Gene ID: 4277
    neXtProt AC: NX_Q29980
    UniProt: Q29980

  • Chr Location
    6p21.33; chr6:31494881-31511124 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040987 Ensembl Gene Model | MGI Sequence Detail 25437 C57BL/6J ±  kb
transcript ENSMUST00000228493 Ensembl | MGI Sequence Detail 2043 Not Applicable  
polypeptide ENSMUSP00000154268 Ensembl | MGI Sequence Detail 355 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
    IPR011161 MHC class I-like antigen recognition-like
    IPR037055 MHC class I-like antigen recognition-like superfamily
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:79325 Kasahara M, et al., A family of MHC class I-like genes located in the vicinity of the mouse leukocyte receptor complex. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13687-92
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory