Tmem259
Gene Detail

Symbol Name ID

Tmem259 transmembrane protein 259 MGI:2177957

Synonyms

membralin, ORF61

Feature Type

protein coding gene

Genetic Map

Chromosome 10

39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr10:79974948-79984330 bp, - strand From VEGA annotation of GRCm38   9383 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:14122  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Tmem259

Human homologs

Human Homolog		TMEM259, transmembrane protein 259
NCBI Gene ID		91304
neXtProt AC		NX_Q4ZIN3
Human Synonyms		ASBABP1, C19orf6, MBRL, MEMBRALIN, R32184_3
Human Chr (Location)		19p13.3; chr19:1009650-1021141 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(3) Gene trapped(2)
 

Mice homozygous for a knock-out allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities.

 

Gene Ontology (GO) classifications

All GO classifications: (4 annotations)

Process	biological_process
Component	integral to membrane, membrane
Function	molecular_function

External Resources: FuncBase

Expression

cDNA source data(99)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(101) Genomic(1) cDNA(99) Other(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000019134 (Evidence)
Ensembl Gene Model	ENSMUSG00000013858 (Evidence)
Entrez Gene	216157 (Evidence)
UniGene	29442
DFCI	TC1581488, TC1598361, TC1600050, TC1604636
NIA Mouse Gene Index	U031998
Consensus CDS Project	CCDS24002.1
International Mouse Knockout Project Status	Tmem259

Sequences

Length	Strain/Species
genomic	OTTMUSG00000019134	VEGA Gene Model | MGI Sequence Detail	9383	C57BL/6J
transcript	OTTMUST00000045865	VEGA | MGI Sequence Detail	2225	Not Applicable
polypeptide	OTTMUSP00000020663	VEGA | MGI Sequence Detail	574	Not Applicable

All sequences(42) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(14 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR019144	Membralin
Protein Ontology	PR:000012036	membralin

References

(Earliest) J:80938 Andersson O, et al., Characterization and expression of the gene encoding membralin, an evolutionary conserved protein expressed in the central nervous system. Brain Res Gene Expr Patterns. 2002 Oct;1(3-4):205-12
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)

Other accession IDs

MGI:2158302