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Tmem259
Gene Detail
Symbol

Name
ID
Tmem259
transmembrane protein 259
MGI:2177957
Synonyms
membralin, ORF61
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:79974948-79984330 bp, - strand
From VEGA annotation of GRCm38

  9383 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14122  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Tmem259

Human
homologs
Human Homolog TMEM259, transmembrane protein 259
NCBI Gene ID 91304
neXtProt AC  NX_Q4ZIN3
Human Synonyms  ASBABP1, C19orf6, MBRL, MEMBRALIN, R32184_3
Human Chr (Location)  19p13.3; chr19:1009651-1021174 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Genomic Mutations involving Tmem259 (1)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities.
 
Interactions
Tmem259 interacts with 47 markers (Mir29b-1, Mir29b-2, Mir29c, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process biological_process
Component integral component of membrane, membrane
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(100)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(102) Genomic(1) cDNA(100) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000019134 (Evidence)
Ensembl Gene ModelENSMUSG00000013858 (Evidence)
Entrez Gene216157 (Evidence)
UniGene29442
DFCITC1600050, TC1604636, TC1598361, TC1581488
NIA Mouse Gene IndexU031998
Consensus CDS ProjectCCDS24002.1
International Mouse Knockout Project StatusTmem259
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019134 VEGA Gene Model | MGI Sequence Detail 9383 C57BL/6J ±  kb
transcript OTTMUST00000045865 VEGA | MGI Sequence Detail 2225 Not Applicable 
polypeptide OTTMUSP00000020663 VEGA | MGI Sequence Detail 574 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(6) UniProt(5)
Polymorphisms
SNPs within 2kb(17 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR019144 Membralin
Protein Ontology PR:000012036 membralin
References
(Earliest) J:80938 Andersson O, et al., Characterization and expression of the gene encoding membralin, an evolutionary conserved protein expressed in the central nervous system. Brain Res Gene Expr Patterns. 2002 Oct;1(3-4):205-12
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)
Other
accession IDs
MGI:2158302

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory