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Tg(Krt1-5-cre/ERT)1Ipc
Transgene Detail
Summary
Symbol: Tg(Krt1-5-cre/ERT)1Ipc
Name: transgene insertion 1, I Pierre Chambon
MGI ID: MGI:2177427
Synonyms: K5-Cre, K5-Cre-ERT, K5CreERT
Transgene: Tg(Krt1-5-cre/ERT)1Ipc  Location: unknown  
Alliance: Tg(Krt1-5-cre/ERT)1Ipc page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Krt1-5-cre/ERT)1Ipc expression driven by 1 gene
 
Mutation detailsThis transgene expresses a tamoxifen-inducible form of cre recombinase under the control of the Krt5 promoter in epidermal tissues. (J:69324)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Krt5 (species not specified)
Summary of all recombinase alleles driven by Krt5.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Tumor Data
List all tumor models in MMHCdb carrying Tg(Krt1-5-cre/ERT)1Ipc
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:69324 Indra AK, et al., Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res. 1999 Nov 15;27(22):4324-7
All:  30 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory