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H1foo
Gene Detail
Symbol

Name
ID
H1foo
H1 histone family, member O, oocyte-specific
MGI:2176207
Synonyms
H1oo
Feature Type
protein coding gene
Genetic Map
Chromosome 6
53.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:115944938-115950236 bp, + strand
From VEGA annotation of GRCm38

  5299 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:51377  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: H1FOO
Gene Tree: H1foo

Human
homologs
H1FOO, H1 histone family, member O, oocyte-specific
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 132243
neXtProt AC: NX_Q8IZA3

Human Synonyms: H1.8, osH1

Human Chr (Location): 3q22.1; chr3:129543214-129551467 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(1) Spontaneous(1) Targeted(5)
Genomic Mutations involving H1foo (1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted mutation exhibit no detectable abnormalities. Oocytes develop normally and no defects in fertility or litter sizes are observed.
 
Interactions
H1foo interacts with 115 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process meiotic cell cycle, negative regulation of stem cell differentiation, ...
Component chromosome, cytoplasm, ...
Function DNA binding, nucleosomal DNA binding
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (54)    Tissues (27)    Images (16)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 17
RNA in situ 6
Northern blot 20
Western blot 4
RT-PCR 7
cDNA source data(51)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase h1foo    NEW 
Molecular
reagents
All nucleic(53) cDNA(51) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000033828 (Evidence)
Ensembl Gene Model ENSMUSG00000042279 (Evidence)
Entrez Gene 171506 (Evidence)
UniGene 21899
DFCI TC1574764
DoTS DT.94174252, DT.101258044
NIA Mouse Gene Index U007302
Consensus CDS Project CCDS20447.1
International Mouse Phenotyping Consortium Status H1foo
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033828 VEGA Gene Model | MGI Sequence Detail 5299 C57BL/6J ±  kb
transcript OTTMUST00000085216 VEGA | MGI Sequence Detail 1113 Not Applicable 
polypeptide OTTMUSP00000046010 VEGA | MGI Sequence Detail 304 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(90 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005818 Histone H1/H5
InterPro IPR011991 Winged helix-turn-helix DNA-binding domain
Protein Ontology PR:000008407 histone H1oo
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:205485 Yu C, et al., CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. Science. 2013 Dec 20;342(6165):1518-21
All references(43)
Other
accession IDs
MGI:2141780

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory