Tg(Wap-cre)11738Mam
Transgene Detail

Summary

• Symbol: Tg(Wap-cre)11738Mam
• Name: transgene insertion 11738, Lothar Hennighausen
• MGI ID: MGI:2176167
• Synonyms: WAP-Cre, WC
• Transgene: Tg(Wap-cre)11738Mam Location: unknown
• Alliance: Tg(Wap-cre)11738Mam page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Wap-cre)11738Mam expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Wap (MGI:98943)

• Mutation details: This transgene directs the expression of Cre recombinase under the control of a 2.6 kb (EcoRI-Asp718) mouse whey acidic protein (Wap) promoter fragment. The Wap promoter directed expression of Cre recombinase in the mammary glands of late pregnant and lactating female mice. No expression was detected in mammary tissue of virgin mice. (J:67925)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Wap (mouse) Summary of all recombinase alleles driven by Wap. Comparative matrix view of recombinase activities Alliance mouse Wap gene page

Disease models

Expression

In Mice Carrying this Mutation:

23 assay results 2 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Wap-cre)11738Mam

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available

References

• Original: J:67925 Wagner KU, et al., Cre-mediated gene deletion in the mammary gland. Nucleic Acids Res. 1997 Nov 1;25(21):4323-30
• All: 114 reference(s)