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Iltifb Gene Detail
Summary
  • Symbol
    Iltifb
  • Name
    interleukin 10-related T cell-derived inducible factor beta
  • Synonyms
    IL-TIFb
  • Feature Type
    protein coding gene
  • IDs
    MGI:2151139
    NCBI Gene: 116849
  • Gene Overview
    MyGene.info: IL22
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr10:118289629-118295038 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 66.70 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    74 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2151139
protein coding gene Chr10:118289629-118295038 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0017741
protein coding gene Chr10:116445728-116450838 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0017705
protein coding gene Chr10:116833170-116838280 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0018160
protein coding gene Chr10:125360602-125364353 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015841
protein coding gene Chr10:110981874-110987000 (+)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0017604
protein coding gene Chr10:115578604-115585626 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0017678
protein coding gene Chr10:121834072-121837605 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017628
protein coding gene Chr10:133140820-133145894 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018201
protein coding gene Chr10:120022682-120028372 (-)
PWK/PhJ MGP_PWKPhJ_G0016874
protein coding gene Chr10:115686885-115691984 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016665
protein coding gene Chr10:118837305-118840846 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IL22, interleukin 22
  • Vertebrate Orthologs
    10
  • Human Ortholog
    IL22, interleukin 22
    Orthology source: HomoloGene, HGNC
  • Synonyms
    IL-21, IL-22, IL-D110, ILTIF, IL-TIF, TIFa, TIFIL-23, zcyto18
  • Links
    NCBI Gene ID: 50616
    neXtProt AC: NX_Q9GZX6
    UniProt: Q9GZX6

  • Chr Location
    12q15; chr12:68248245-68253501 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 116849 NCBI Gene Model | MGI Sequence Detail 5410 C57BL/6J ±  kb
transcript NM_054079 RefSeq | MGI Sequence Detail 1111 C57BL/6  
polypeptide Q9JJY8 UniProt | EBI | MGI Sequence Detail 179 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory