Aipl1
Gene Detail

Symbol Name ID

Aipl1 aryl hydrocarbon receptor-interacting protein-like 1 MGI:2148800

Synonyms

A930007I01Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 11

43.81 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr11:72027963-72037509 bp, - strand From VEGA annotation of GRCm38   9547 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:22806  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Aipl1

Human homologs

Human Homolog		AIPL1, aryl hydrocarbon receptor interacting protein-like 1
NCBI Gene ID		23746
neXtProt AC		NX_Q9NZN9
Human Synonyms		AIPL2, LCA4
Human Chr (Location)		17p13.1; chr17:6327059-6338519 (-)  GRCh37.p10
Disease Associations		(2) Diseases Associated with Human AIPL1

Alleles and phenotypes

All alleles(4) : Targeted(4)
 

Homozygous null mice display complete retinal degeneration and a lack of electroretinographic responses. Homozygous hypomorphic mutants display less severe retinal degeneration and impaired electroretinographic responses.

 
Human Diseases Modeled Using Mouse Aipl1 (1)    Alleles Annotated to Human Diseases(3)    Phenotype Images(3)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	negative regulation of apoptotic process, phototransduction, visible light, ...
Component	cytoplasm, nucleus, ...
Function	farnesylated protein binding

External Resources: FuncBase

Expression

cDNA source data(33)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(33) cDNA(33)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000006096 (Evidence)
Ensembl Gene Model	ENSMUSG00000040554 (Evidence)
Entrez Gene	114230 (Evidence)
UniGene	95707
DFCI	TC1585962, TC1614228
DoTS	DT.87035345, DT.94292970
NIA Mouse Gene Index	U033020
Consensus CDS Project	CCDS24976.1
International Mouse Knockout Project Status	Aipl1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000006096	VEGA Gene Model | MGI Sequence Detail	9547	C57BL/6J
transcript	OTTMUST00000013772	VEGA | MGI Sequence Detail	2309	Not Applicable
polypeptide	OTTMUSP00000006382	VEGA | MGI Sequence Detail	328	Not Applicable

All sequences(28) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(56 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023114	Elongated TPR repeat-containing domain
InterPro	IPR001179	Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain
InterPro	IPR011990	Tetratricopeptide-like helical
InterPro	IPR019734	Tetratricopeptide repeat
InterPro	IPR013026	Tetratricopeptide repeat-containing domain
InterPro	IPR013105	Tetratricopeptide TPR2
Protein Ontology	PR:000003876	aryl-hydrocarbon-interacting protein-like 1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:171900 Christiansen JR, et al., RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8862-6
All references(35)

Other accession IDs

MGI:1925019