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Acaa1a Gene Detail
Summary
  • Symbol
    Acaa1a
  • Name
    acetyl-Coenzyme A acyltransferase 1A
  • Synonyms
    Acaa1, D9Ertd25e, MGC:7090, peroxisomal 3-ketoacyl-CoA thiolase, PTL, thiolase A
  • Feature Type
    protein coding gene
  • IDs
    MGI:2148491
    NCBI Gene: 113868
  • Gene Overview
    MyGene.info: ACAA1
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr9:119339676-119350299 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10624 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 71.33 cM, cytoband F4
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    ACAA1, acetyl-CoA acyltransferase 1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ACAA1, acetyl-CoA acyltransferase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ACAA, PTHIO, THIO
  • Links
    NCBI Gene ID: 30
    neXtProt AC: NX_P09110
    UniProt: P09110

  • Chr Location
    3p22.2; chr3:38122710-38137242 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000042191 VEGA Gene Model | MGI Sequence Detail 10624 C57BL/6J ±  kb
    transcript OTTMUST00000110753 VEGA | MGI Sequence Detail 1762 Not Applicable  
    polypeptide OTTMUSP00000061838 VEGA | MGI Sequence Detail 424 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      146 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 189
      cDNA 188
      Primer pair 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1098606
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 6
      Gene Ontology 8
      Phenotypes 6
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    07/31/2018
    MGI 6.12
    The Jackson Laboratory