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Acaa1a
Gene Detail
Symbol

Name
ID
Acaa1a
acetyl-Coenzyme A acyltransferase 1A
MGI:2148491
Synonyms
Acaa1, D9Ertd25e, MGC:7090, peroxisomal 3-ketoacyl-CoA thiolase, PTL, thiolase A
Feature Type
protein coding gene
Genetic Map
Chromosome 9
71.33 cM, cytoband F4
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr9:119339676-119350299 bp, + strand
From VEGA annotation of GRCm38

  10624 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37497  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: acetyl-CoA acetyltransferase
Gene Tree: Acaa1a

Human
homologs
Human Homolog ACAA1, acetyl-CoA acyltransferase 1
NCBI Gene ID 30
neXtProt AC  NX_P09110
Human Synonyms  ACAA, PTHIO, THIO
Human Chr (Location)  3p22.2; chr3:38122710-38137242 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Acaa1a interacts with 87 markers (Mir20a, Mir20b, Mir27a, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (220)    Tissues (117)    Images (42)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 190
Northern blot 15
Western blot 15
cDNA source data(186)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(189) cDNA(188) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000042191 (Evidence)
Ensembl Gene ModelENSMUSG00000036138 (Evidence)
Entrez Gene113868 (Evidence)
UniGene205266
NIA Mouse Gene IndexU011135
EC2.3.1.16
Consensus CDS ProjectCCDS23613.1
International Mouse Knockout Project StatusAcaa1a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042191 VEGA Gene Model | MGI Sequence Detail 10624 C57BL/6J ±  kb
transcript OTTMUST00000110753 VEGA | MGI Sequence Detail 1762 Not Applicable 
polypeptide OTTMUSP00000061838 VEGA | MGI Sequence Detail 424 Not Applicable 

For the selected sequences
All sequences(70) RefSeq(6) UniProt(17)
Polymorphisms
SNPs within 2kb(156 from dbSNP Build 137)    SNPs within 2kb including multiple locations(170)
Protein-related
information
ResourceIDDescription
InterPro IPR002155 Thiolase
InterPro IPR020610 Thiolase, active site
InterPro IPR020615 Thiolase, acyl-enzyme intermediate active site
InterPro IPR020613 Thiolase, conserved site
InterPro IPR020617 Thiolase, C-terminal
InterPro IPR016039 Thiolase-like
InterPro IPR016038 Thiolase-like, subgroup
InterPro IPR020616 Thiolase, N-terminal
Protein Ontology PR:000004540 3-ketoacyl-CoA thiolase A, peroxisomal
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607
All references(43)
Other
accession IDs
MGI:1098606

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory