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Kank1
Gene Detail
Symbol

Name
ID
Kank1
KN motif and ankyrin repeat domains 1
MGI:2147707
Synonyms
A930031B09Rik, Ankrd15, D330024H06Rik, mKIAA0172
Feature Type
protein coding gene
Genetic Map
Chromosome 19
20.33 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:25236975-25434496 bp, + strand
From VEGA annotation of GRCm38

  197522 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:17706  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: KANK1
Gene Tree: Kank1

Human
homologs
KANK1, KN motif and ankyrin repeat domains 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 23189
neXtProt AC: NX_Q14678

Human Synonyms: ANKRD15, CPSQ2, KANK

Human Chr (Location): 9p24.3; chr9:470294-746106 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human KANK1

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(11) Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Kank1 interacts with 182 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process negative regulation of actin filament polymerization, negative regulation of cell migration, ...
Component cytoplasm, nucleus, ...
Function beta-catenin binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (496)    Tissues (100)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 496
cDNA source data(69)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase kank1    NEW 
Molecular
reagents
All nucleic(69) cDNA(69)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000033447 (Evidence)
Ensembl Gene Model ENSMUSG00000032702 (Evidence)
Entrez Gene 107351 (Evidence)
UniGene 260722
DFCI TC1577831, TC1597490, TC1602730, TC1774029
DoTS DT.101723838, DT.484299, DT.91371222
NIA Mouse Gene Index U019320
Consensus CDS Project CCDS37944.1
International Mouse Phenotyping Consortium Status Kank1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033447 VEGA Gene Model | MGI Sequence Detail 197522 C57BL/6J ±  kb
transcript OTTMUST00000084032 VEGA | MGI Sequence Detail 5637 Not Applicable 
polypeptide OTTMUSP00000045223 VEGA | MGI Sequence Detail 1360 Not Applicable 

For the selected sequences
All sequences(65) RefSeq(18) UniProt(8)
Polymorphisms
SNPs within 2kb(2085 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002110 Ankyrin repeat
InterPro IPR020683 Ankyrin repeat-containing domain
InterPro IPR021939 Kank N-terminal motif
Protein Ontology PR:000009239 KN motif and ankyrin repeat domain-containing protein 1
References
(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:209112 Shimizu H, et al., The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
All references(39)
Other
accession IDs
MGI:1925073, MGI:2147636

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory