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Parp12 Gene Detail
Summary
  • Symbol
    Parp12
  • Name
    poly (ADP-ribose) polymerase family, member 12
  • Synonyms
    Zc3hdc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143990
    NCBI Gene: 243771
  • Gene Overview
    MyGene.info: PARP12
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:39086412-39118349 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 17.85 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    49 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143990
protein coding gene Chr6:39086410-39118349 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030593
protein coding gene Chr6:37439667-37473712 (-)
A/J MGP_AJ_G0030566
protein coding gene Chr6:35805616-35839382 (-)
AKR/J MGP_AKRJ_G0030493
protein coding gene Chr6:36949430-36981370 (-)
BALB/cJ MGP_BALBcJ_G0030576
protein coding gene Chr6:36020087-36052165 (-)
C3H/HeJ MGP_C3HHeJ_G0030289
protein coding gene Chr6:36956664-36991404 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031030
protein coding gene Chr6:38358868-38395560 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028242
protein coding gene Chr6:33711993-33746103 (-)
CAST/EiJ MGP_CASTEiJ_G0029691
protein coding gene Chr6:36859897-36895684 (-)
CBA/J MGP_CBAJ_G0030267
protein coding gene Chr6:39863480-39899301 (-)
DBA/2J MGP_DBA2J_G0030411
protein coding gene Chr6:35634584-35668589 (-)
FVB/NJ MGP_FVBNJ_G0030365
protein coding gene Chr6:35414303-35447153 (-)
LP/J MGP_LPJ_G0030498
protein coding gene Chr6:37467221-37502793 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030401
protein coding gene Chr6:42233495-42267519 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031060
protein coding gene Chr6:36880154-36915463 (-)
PWK/PhJ MGP_PWKPhJ_G0029405
protein coding gene Chr6:35305504-35338652 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029241
protein coding gene Chr6:36620666-36653473 (-)
WSB/EiJ MGP_WSBEiJ_G0029767
protein coding gene Chr6:36829213-36862283 (-)



Homology
more
  • Human Ortholog
    PARP12, poly(ADP-ribose) polymerase family member 12
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PARP12, poly(ADP-ribose) polymerase family member 12
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARTD12, MST109, MSTP109, ZC3H1, ZC3HDC1
  • Links
    NCBI Gene ID: 64761
    neXtProt AC: NX_Q9H0J9
    UniProt: Q9H0J9

  • Chr Location
    7q34; chr7:140023744-140063721 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11236
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PARP12
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 243771 NCBI Gene Model | MGI Sequence Detail 31938 C57BL/6J ±  kb
transcript NM_172893 RefSeq | MGI Sequence Detail 3322 C57BL/6  
polypeptide Q8BZ20 UniProt | EBI | MGI Sequence Detail 711 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 101
    cDNA 100
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1889366
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:86519 Katoh M, et al., Identification and characterization of human TIPARP gene within the CCNL amplicon at human chromosome 3q25.31. Int J Oncol. 2003 Aug;23(2):541-7
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory