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L3mbtl3
Gene Detail
Symbol

Name
ID
L3mbtl3
l(3)mbt-like 3 (Drosophila)
MGI:2143628
Synonyms
MBT-1, mKIAA1798
Feature Type
protein coding gene
Genetic Map
Chromosome 10
13.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:26274468-26375185 bp, - strand
From VEGA annotation of GRCm38

  100718 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18226  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: L3MBTL3
Gene Tree: L3mbtl3

Human
homologs
L3MBTL3, l(3)mbt-like 3 (Drosophila)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 84456
neXtProt AC: NX_Q96JM7

Human Synonyms: MBT1, MBT-1

Human Chr (Location): 6q23; chr6:129978804-130141449 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(3) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation die between E17.5 ? 19.5 due to disturbed erythropoiesis which result in anemia.
 
Interactions
L3mbtl3 interacts with 309 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process chromatin modification, erythrocyte maturation, ...
Component nucleus
Function protein binding
External Resources: FuncBase
Expression
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase l3mbtl3    NEW 
Molecular
reagents
All nucleic(12) cDNA(12)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000037127 (Evidence)
Ensembl Gene Model ENSMUSG00000039089 (Evidence)
Entrez Gene 237339 (Evidence)
DFCI TC1660759, TC1589255, TC1578124, TC1606058
DoTS DT.97338926, DT.91580752, DT.490661, DT.40137571, DT.101736153
NIA Mouse Gene Index U031628
Consensus CDS Project CCDS23756.1
International Mouse Phenotyping Consortium Status L3mbtl3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037127 VEGA Gene Model | MGI Sequence Detail 100718 C57BL/6J ±  kb
transcript OTTMUST00000095593 VEGA | MGI Sequence Detail 3411 Not Applicable 
polypeptide OTTMUSP00000053340 VEGA | MGI Sequence Detail 883 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(16) UniProt(2)
Polymorphisms
SNPs within 2kb(486 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004092 Mbt repeat
InterPro IPR001660 Sterile alpha motif domain
InterPro IPR013761 Sterile alpha motif/pointed domain
InterPro IPR021129 Sterile alpha motif, type 1
Protein Ontology PR:000009642 lethal(3)malignant brain tumor-like protein 3
References
(Earliest) J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory