L3mbtl3
Gene Detail

Symbol Name ID

L3mbtl3 l(3)mbt-like 3 (Drosophila) MGI:2143628

Synonyms

MBT-1, mKIAA1798

Feature Type

protein coding gene

Genetic Map

Chromosome 10

13.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr10:26274468-26375185 bp, - strand From VEGA annotation of GRCm38   100718 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:18226  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: L3mbtl3

Human homologs

Human Homolog		L3MBTL3, l(3)mbt-like 3 (Drosophila)
NCBI Gene ID		84456
neXtProt AC		NX_Q96JM7
Human Synonyms		MBT1, MBT-1, RP11-73O6.1
Human Chr (Location)		6q23; chr6:130339728-130462594 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(6) : Targeted(3) Gene trapped(3)
 

Mice homozygous for a null mutation die between E17.5 ? 19.5 due to disturbed erythropoiesis which result in anemia.

 

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	chromatin modification, regulation of transcription, DNA-dependent, ...
Component	nucleus

External Resources: FuncBase

Expression

cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(12) cDNA(12)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000037127 (Evidence)
Ensembl Gene Model	ENSMUSG00000039089 (Evidence)
Entrez Gene	237339 (Evidence)
DFCI	TC1578124, TC1589255, TC1606058, TC1660759
DoTS	DT.101736153, DT.40137571, DT.490661, DT.91580752, DT.97338926
NIA Mouse Gene Index	U031628
Consensus CDS Project	CCDS23756.1
International Mouse Knockout Project Status	L3mbtl3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000037127	VEGA Gene Model | MGI Sequence Detail	100718	C57BL/6J
transcript	OTTMUST00000095593	VEGA | MGI Sequence Detail	3411	Not Applicable
polypeptide	OTTMUSP00000053340	VEGA | MGI Sequence Detail	883	Not Applicable

All sequences(43) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(460 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004092	Mbt repeat
InterPro	IPR001660	Sterile alpha motif domain
InterPro	IPR013761	Sterile alpha motif/pointed domain
InterPro	IPR021129	Sterile alpha motif, type 1
Protein Ontology	PR:000009642	lethal(3)malignant brain tumor-like protein 3

References

(Earliest) J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(28)