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A4gnt
Gene Detail
Symbol

Name
ID
A4gnt
alpha-1,4-N-acetylglucosaminyltransferase
MGI:2143261
Synonyms
alpha4GnT, LOC333424
Feature Type
protein coding gene
Genetic Map
Chromosome 9
51.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:99612502-99622367 bp, + strand
From VEGA annotation of GRCm38

  9866 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:87446  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 20 western clawed frog

HCOP human homology predictions: A4GNT
Gene Tree: A4gnt

Human
homologs
A4GNT, alpha-1,4-N-acetylglucosaminyltransferase
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 51146
neXtProt AC: NX_Q9UNA3

Human Synonyms: alpha4GnT

Human Chr (Location): 3p14.3; chr3:138123718-138132387 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from APF )
 
Mice homozygous for a knock-out allele exhibit gastric adenocarcinoma with increased cell proliferation, angiogenesis, inflammation and gastric mucosal thickness.
 
Phenotype Images(3)
Interactions
A4gnt interacts with 174 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase a4gnt    NEW 
Molecular
reagents
All nucleic(6) Genomic(1) cDNA(5)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000048239 (Evidence)
Ensembl Gene Model ENSMUSG00000037953 (Evidence)
Entrez Gene 333424 (Evidence)
UniGene 297753
DoTS DT.55175215
NIA Mouse Gene Index U111114
Consensus CDS Project CCDS40740.1
International Mouse Phenotyping Consortium Status A4gnt
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048239 VEGA Gene Model | MGI Sequence Detail 9866 C57BL/6J ±  kb
transcript OTTMUST00000123834 VEGA | MGI Sequence Detail 2757 Not Applicable 
polypeptide OTTMUSP00000067519 VEGA | MGI Sequence Detail 341 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(8) UniProt(1)
Polymorphisms
SNPs within 2kb(116 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007652 Alpha 1,4-glycosyltransferase domain
InterPro IPR007577 Glycosyltransferase, DXD sugar-binding motif
Protein Ontology PR:000003517 alpha-1,4-N-acetylglucosaminyltransferase
References
(Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:184485 Karasawa F, et al., Essential role of gastric gland mucin in preventing gastric cancer in mice. J Clin Invest. 2012 Mar 1;122(3):923-34
All references(23)
Other
accession IDs
MGI:2685644

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory