Tmem40 Gene Detail

Summary

• Symbol
  Tmem40
• Name
  transmembrane protein 40
• Synonyms
  9030407H20Rik

• Feature Type
  protein coding gene
• IDs
  MGI:2137870
  NCBI Gene: 94346

Location & Maps

• Sequence Map
  Chr6:115729131-115762410 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    33280 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, 53.68 cM
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  TMEM40, transmembrane protein 40

• Vertebrate Orthologs
  7

• Human Ortholog
  TMEM40, transmembrane protein 40
  Orthology source: HomoloGene, HGNC
• Links
  HGNC:25620

  NCBI Gene ID: 55287

  neXtProt AC: NX_Q8WWA1

  UniProt: Q8WWA1

  
  
• Chr Location
  3p25.2; chr3:12733530-12769457 (-)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 10124
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 macaque, rhesus
  
• HCOP
  human homology predictions: TMEM40
• Gene Tree
  Tmem40
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  41
• Gene trapped
  38
• Spontaneous
  1
• Targeted
  2
• Genomic Mutations
  1 involving Tmem40
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  38 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  1

• External Resources
  FuncBase

Expression

• Assay Results
  26
• Tissues
  7
• cDNA Data
  24
• Literature Summary
  2

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase tmem40

Interactions

• Tmem40 interacts with 58 markers (Mir7-2, Mir7b, Mir9-1, ...) View All

Sequences &
Gene Models

• All Sequences
  56
• RefSeq
  20
• UniProt
  3
• CCDS
  CCDS39601.1, CCDS51878.1, CCDS51879.1
• UniGene
  29739

• VEGA
  OTTMUSG00000024222 (Evidence)
• Ensembl
  ENSMUSG00000059900 (Evidence)
• NCBI Gene
  94346

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000024222	VEGA Gene Model | MGI Sequence Detail	33280	C57BL/6J
transcript	OTTMUST00000059275	VEGA | MGI Sequence Detail	1554	Not Applicable
polypeptide	OTTMUSP00000028822	VEGA | MGI Sequence Detail	266	Not Applicable

Polymorphisms

• SNPs within 2kb
  465 from dbSNP Build 142

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000029814 transmembrane protein 40
  (term hierarchy)
• InterPro Domains
  IPR026181 Transmembrane protein 40

Molecular
Reagents

• All nucleic 24

  cDNA 24

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:2141619

References

• Summaries
  All 28

  Developmental Gene Expression 2

  Gene Ontology 1

  Phenotypes 6
• Earliest
  J:67747 Thut CJ, et al., A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582