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Klra21 Gene Detail
Summary
  • Symbol
    Klra21
  • Name
    killer cell lectin-like receptor subfamily A, member 21
  • Synonyms
    Ly49u
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136938
  • Member of
    Klra cluster
  • Alliance
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 6, Syntenic
  • Mapping Data
    1 experiment
Homology
less
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
transcript AF288380 GenBank | EMBL | DDBJ | MGI Sequence Detail 1150 129P3/J  
polypeptide Q9JHV1 UniProt | EBI | MGI Sequence Detail 266 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR016187 C-type lectin fold
    IPR001304 C-type lectin-like
    IPR016186 C-type lectin-like/link domain superfamily
    IPR013600 Ly49-like, N-terminal
    IPR033992 Natural killer cell receptor-like, C-type lectin-like domain
Molecular
Reagents
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  • Microarray probesets 1
References
more
  • Summaries
    All 6
    Gene Ontology 1
  • Earliest
    J:68623 Makrigiannis AP, et al., Class I MHC-binding characteristics of the 129/J Ly49 repertoire. J Immunol. 2001 Apr 15;166(8):5034-43
  • Latest
    J:99309 Desrosiers MP, et al., Epistasis between mouse Klra and major histocompatibility complex class I loci is associated with a new mechanism of natural killer cell-mediated innate resistance to cytomegalovirus infection. Nat Genet. 2005 Jun;37(6):593-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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Funding Information
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory